{
  "docId": "019de074-05b7-71fd-bc3c-27f1b7be8924",
  "docSlug": "c3cb552ef3a6b077a714c97117e1fe86",
  "documentTitle": "Mink Therapeutics | Investor Day Presentation Deck | 92 slides",
  "authorId": "mink-therapeutics",
  "authorName": "MiNK Therapeutics",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-11-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 21,
  "pageCount": 92,
  "prevPage": 20,
  "nextPage": 22,
  "slideType": "key_messages",
  "function": "establish_context",
  "density": "balanced",
  "nDataPoints": 0,
  "notes": "The diagram uses a hub-and-spoke model to show iNKT cells at the center modulating innate (Dendritic, Macrophage, NK) and adaptive (T, B) cells.",
  "elementsJson": null,
  "metadataConfidence": 0.95,
  "imagePath": null,
  "slideHref": "/slides/019de074-05b7-71fd-bc3c-27f1b7be8924/21",
  "deckHref": "/decks/019de074-05b7-71fd-bc3c-27f1b7be8924",
  "deckJsonHref": "/decks/019de074-05b7-71fd-bc3c-27f1b7be8924.json",
  "deckAnchorHref": "/decks/019de074-05b7-71fd-bc3c-27f1b7be8924#slide-21",
  "components": [
    {
      "bbox": {
        "h": 0.72,
        "w": 0.68,
        "x": 0.03,
        "y": 0.18
      },
      "kind": "diagram",
      "text": "iNKT cells at center modulating innate and adaptive immune cells",
      "attrs": null,
      "subkind": "hub-spoke",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b865e635-51c6-46bc-a80c-192f4ea4694d",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.19,
        "x": 0.79,
        "y": 0.87
      },
      "kind": "image",
      "text": "University of Manchester logo",
      "attrs": null,
      "subkind": "logo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "932ed588-817a-4dff-928b-7681530e71ea",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.65,
        "w": 0.24,
        "x": 0.74,
        "y": 0.2
      },
      "kind": "list",
      "text": "Rapid Response: Distinct T cells that possess the effector function of adaptive immune cells, but also the rapid activation kinetics of innate immune cells. Potent Activity: While rare in circulation, iNKTs can amplify & accelerate immune surveillance and response. Flexible Platform: Polarization of iNKTs towards pro- or anti-inflammatory states can tailor activity for specific indications",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b5af0dbc-039c-4448-82b6-e726b9b83292",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.12,
        "w": 0.65,
        "x": 0.03,
        "y": 0.05
      },
      "kind": "title",
      "text": "iNKT Cells are Distinct in the Cell Therapy Landscape, Combining both Innate and Adaptive Immunity",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "13ed636e-3a6f-4846-8e54-286cacf33a56",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [
    {
      "name": "hub-spoke",
      "slug": null,
      "matchId": "724861d2-4047-4402-b726-6520333e0e1f",
      "evidence": "Central iNKT cell node with directional arrows to peripheral immune cell types",
      "confidence": 0.9
    }
  ],
  "arcBeats": [
    {
      "to": 22,
      "from": 18,
      "beatId": "712f2bca-7294-4694-b198-ee95567c1d0b",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Proposed Solution",
      "beatSlug": null,
      "evidence": "The presentation introduces iNKT cells as a potential solution",
      "position": 1,
      "confidence": 0.8,
      "parentBeatName": null,
      "parentBeatSlug": null
    }
  ],
  "loops": [
    {
      "to": 22,
      "from": 17,
      "name": "Logic Chain",
      "slug": "01-logic-chain",
      "bestFor": "Skeptical audiences, controversial recommendations, rigorous analysis",
      "matchId": "564e86af-6c91-4448-9e43-c23c0dddd4ef",
      "evidence": "The presentation builds a logical argument for iNKT cells' potential",
      "position": 0,
      "objective": "Establishing the rationale for iNKT cells in cancer treatment",
      "structure": "Premise 1 (Accepted truth) -> Premise 2 (Observed fact) -> Therefore... (Inevitable conclusion)",
      "confidence": 0.7,
      "description": "Build an airtight chain of logic where each premise leads inevitably to the conclusion"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}