{
  "docId": "019de073-e8d5-735f-8ffd-8a5102406a96",
  "docSlug": "3003a94fa3be7c8f2ff0fbac5a54b26e",
  "documentTitle": "Arbutus Biopharma | Results Presentation Deck | 15 slides",
  "authorId": "arbutus-biopharma",
  "authorName": "Arbutus Biopharma",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-11-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 14,
  "pageCount": 15,
  "prevPage": 13,
  "nextPage": 15,
  "slideType": "executive_summary",
  "function": "summarize",
  "density": "balanced",
  "nDataPoints": 0,
  "notes": null,
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de073-e8d5-735f-8ffd-8a5102406a96/14",
  "deckHref": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96",
  "deckJsonHref": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96.json",
  "deckAnchorHref": "/decks/019de073-e8d5-735f-8ffd-8a5102406a96#slide-14",
  "components": [
    {
      "bbox": {
        "h": 0.45,
        "w": 0.848,
        "x": 0.076,
        "y": 0.225
      },
      "kind": "list",
      "text": "Oral small-molecule PD-L1 inhibitors have been identified which function through a novel internalization mechanism distinct from antibody approaches\nCombination treatment with AB-101 and HBV-targeting siRNA resulted in the activation of HBV-specific T cell and humoral responses in an AAV-HBV mouse model\nThis favorable preclinical profile suggests this combination treatment strategy may provide additional benefit in increasing HBV immune responses, a key driver of CHB functional cure",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "16902d83-c0cb-4789-9efe-8ea8d640d8b1",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.055,
        "w": 0.245,
        "x": 0.076,
        "y": 0.076
      },
      "kind": "title",
      "text": "AB-101: Summary",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "86ace89a-3014-42d9-b696-94d81500821d",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Executive summary",
      "slug": "executive-summary",
      "agent": null,
      "layer": "slide",
      "matchId": "c5d9725b-fc9f-446c-8628-371735337546",
      "evidence": "Oral small-molecule PD-L1 inhibitors have been identified which function through a novel internalization mechanism distinct from antibody approaches",
      "confidence": 0.9
    }
  ],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}