{
  "docId": "019de073-bcea-715e-8f3b-2af68c1e6615",
  "docSlug": "cfcb19cc2b89b85461a28b4631a8b033",
  "documentTitle": "Hepion Pharmaceuticals | Results Presentation Deck | 34 slides",
  "authorId": "hepion-pharmaceuticals",
  "authorName": "Hepion Pharmaceuticals",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7761332,
  "pageNumber": 26,
  "pageCount": 34,
  "prevPage": 25,
  "nextPage": 27,
  "slideType": "appendix_methodology",
  "function": "plan_implementation",
  "density": "dense",
  "nDataPoints": 6,
  "notes": "The slide outlines a randomized clinical trial structure with three dosing arms and a follow-up period.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de073-bcea-715e-8f3b-2af68c1e6615/26",
  "deckHref": "/decks/019de073-bcea-715e-8f3b-2af68c1e6615",
  "deckJsonHref": "/decks/019de073-bcea-715e-8f3b-2af68c1e6615.json",
  "deckAnchorHref": "/decks/019de073-bcea-715e-8f3b-2af68c1e6615#slide-26",
  "components": [
    {
      "bbox": {
        "h": 0.45,
        "w": 0.65,
        "x": 0.06,
        "y": 0.35
      },
      "kind": "diagram",
      "text": "Trial timeline showing randomization at day 1, dosing until day 120, and follow-up until day 134.",
      "attrs": null,
      "subkind": "timeline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f952be7b-0931-4798-87e1-1a62e3b14644",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.8,
        "x": 0.06,
        "y": 0.85
      },
      "kind": "list",
      "text": "Subjects identified from historical biopsy or by meeting AGILE 3+ criteria for F3. Subjects who complete study will be considered for enrollment into ASCEND-NASH 2b",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "2fc8ca12-3653-49aa-b583-c3157f9a26eb",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.3,
        "w": 0.2,
        "x": 0.73,
        "y": 0.35
      },
      "kind": "list",
      "text": "Endpoints: Efficacy (HepQuant SHUNT, NASH NIMs), Safety, Tolerability, Pharmacokinetics",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f5137b88-822e-4ef6-8623-928d2fd43042",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.88,
        "x": 0.06,
        "y": 0.12
      },
      "kind": "paragraph",
      "text": "Primary Objective: Evaluate the change in hepatic function with once daily (QD) 75 mg, 150 mg, and 225 mg doses of rencofilstat in subjects with NASH F3 fibrosis using the HepQuant SHUNT test.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "09a06d57-20b3-473c-a820-a8fdd83eec73",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.45,
        "x": 0.06,
        "y": 0.06
      },
      "kind": "title",
      "text": "Phase 2 'ALTITUDE-NASH' (Liver Function Trial)",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8494db43-e785-4245-8aef-1c53bd32689e",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [
    {
      "name": "gantt-chart",
      "slug": null,
      "matchId": "c58bcf28-1dc8-45a0-9641-209075e64ae3",
      "evidence": "The timeline visualization represents a clinical trial schedule.",
      "confidence": 0.8
    }
  ],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}