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  "documentTitle": "Genprex | Investor Presentation Deck | 39 slides",
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  "notes": "Includes a scientific diagram illustrating the alpha-to-beta cell reprogramming process.",
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      "text": "A Phase 1 clinical trial could be the first-ever gene therapy tested in humans for diabetes.",
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      "text": "Diagram showing intraductal infusion of Pdx1- and MafA-expressing AAV, alpha-to-beta cell reprogramming, and transition from beta-cell deficiency to restored beta-cell mass.",
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      "text": "Novel infusion process uses an endoscope and an AAV vector to deliver the Pdx1 + MafA genes to the pancreas. In T1D, it transforms alpha cells in the pancreas into functional beta-like cells. In T2D, it may replenish and rejuvenate beta cells. In vivo, preclinical studies show that GPX-002 restored normal blood glucose levels for an extended period of time.",
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      "text": "Image source: Osipovich, Anna & Magnuson, Mark. (2018). Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes. Cell Stem Cell. 22. 12-13. 10.1016/j.stem.2017.12.012.",
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      "text": "REPROGRAMS AND RESTORES CELL FUNCTION",
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      "text": "GPX-002 REPLENISHES LEVELS OF INSULIN",
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