{
  "docId": "019de073-bad9-7032-8a81-e4ebe475dedb",
  "docSlug": "033dbe0b064db9b5c6a8c7c8096ccb5c",
  "documentTitle": "Genprex | Investor Presentation Deck | 44 slides",
  "authorId": "genprex",
  "authorName": "Genprex",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 20,
  "pageCount": 44,
  "prevPage": 19,
  "nextPage": 21,
  "slideType": "traction",
  "function": "show_traction",
  "density": "dense",
  "nDataPoints": 10,
  "notes": "The slide uses TUSC2 as the synonym for REQORSA in the charts. Data shows statistical significance (p-values) for the triple combination.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de073-bad9-7032-8a81-e4ebe475dedb/20",
  "deckHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb",
  "deckJsonHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb.json",
  "deckAnchorHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb#slide-20",
  "components": [
    {
      "bbox": {
        "h": 0.45,
        "w": 0.4,
        "x": 0.52,
        "y": 0.35
      },
      "kind": "chart",
      "text": "Tumor intensity at week 4 post-treatment across five groups.",
      "attrs": null,
      "subkind": "bar-vertical",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "9521b16a-bd91-4a46-87c0-0747becdd607",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.45,
        "w": 0.4,
        "x": 0.06,
        "y": 0.35
      },
      "kind": "chart",
      "text": "Tumor growth over time (D14-D35) for four treatment groups.",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "999ecbf4-82f1-4355-a769-a8245d2a8c08",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.9,
        "x": 0.06,
        "y": 0.19
      },
      "kind": "list",
      "text": "REQORSA enhances the efficacy of chemo-immunotherapy on KL-mutant lung metastases in humanized mice.\nTriple combination demonstrated strong antitumor efficacy and induced robust antitumor immunity in KRAS-LKB1 (KL)-mutant NSCLC in clinically relevant humanized mice models.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8bd8b389-67ed-417c-be01-33a5c112828f",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.3,
        "x": 0.06,
        "y": 0.14
      },
      "kind": "paragraph",
      "text": "REQORSA + Keytruda + Chemo",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "270dc822-c84d-4f5e-957a-083f203a0903",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.6,
        "x": 0.15,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Pembrolizumab is the generic name of Keytruda. REQORSA referred to as TUSC2 in figures.",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c56c368e-bab7-4493-8f6a-aa058fbabc2b",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.8,
        "x": 0.06,
        "y": 0.06
      },
      "kind": "title",
      "text": "AACR 21: REQORSA MAY ENHANCE FIRST-LINE STANDARD OF CARE",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "40daf458-6b23-4fab-bbed-d1411a444303",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 20,
      "from": 9,
      "beatId": "727dc990-5781-44c1-9860-17b14bcb030f",
      "arcName": "Monroe's Motivated Sequence",
      "arcSlug": "monroes-sequence",
      "beatName": "Satisfaction",
      "beatSlug": "monroes-sequence-satisfaction",
      "evidence": "Slides 9-20: Solution and traction for REQORSA therapy",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Turn",
      "parentBeatSlug": "turn"
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}