{
  "docId": "019de073-bad9-7032-8a81-e4ebe475dedb",
  "docSlug": "033dbe0b064db9b5c6a8c7c8096ccb5c",
  "documentTitle": "Genprex | Investor Presentation Deck | 44 slides",
  "authorId": "genprex",
  "authorName": "Genprex",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 19,
  "pageCount": 44,
  "prevPage": 18,
  "nextPage": 20,
  "slideType": "solution",
  "function": "present_solution",
  "density": "dense",
  "nDataPoints": 6,
  "notes": "The slide uses bioluminescence imaging and bar charts to show immune cell population changes (T cells, NK cells, MDSC, DC).",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de073-bad9-7032-8a81-e4ebe475dedb/19",
  "deckHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb",
  "deckJsonHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb.json",
  "deckAnchorHref": "/decks/019de073-bad9-7032-8a81-e4ebe475dedb#slide-19",
  "components": [
    {
      "bbox": {
        "h": 0.7,
        "w": 0.4,
        "x": 0.55,
        "y": 0.2
      },
      "kind": "chart",
      "text": "Bar charts showing percentages of T cells, Active T cells, NK cells, Active NK cells, MDSC, and DC.",
      "attrs": null,
      "subkind": "bar-vertical",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "23b3865a-8829-4df7-aa20-c7afc0547f8a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.5,
        "w": 0.35,
        "x": 0.15,
        "y": 0.2
      },
      "kind": "image",
      "text": "Bioluminescence imaging of mice treated with Control, TUSC2, Pembro, and Combination.",
      "attrs": null,
      "subkind": "illustration",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d3774962-fa2f-4d81-aa64-25c9eb19f774",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.3,
        "x": 0.15,
        "y": 0.75
      },
      "kind": "paragraph",
      "text": "The independent immunologic effects of REQORSA and Keytruda create synergy by adding increased immunologic attack on the tumor to PD-1 inhibition.",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c4ac3c58-55d9-42b7-9d5f-c2980ee8d40d",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.7,
        "x": 0.15,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Pembrolizumab is the generic name of Keytruda. REQORSA referred to as TUSC2 in figures.",
      "attrs": {
        "numbered": true
      },
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "1b2aca4b-99e4-48a9-9632-c7fa16283d18",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.03,
        "w": 0.7,
        "x": 0.15,
        "y": 0.12
      },
      "kind": "title",
      "text": "REQORSA IS SYNERGISTIC WITH ANTI-PD1 IN A HUMANIZED MOUSE MODEL OF LUNG CANCER",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "05a753e1-ad65-48fa-acce-2b111461912d",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.7,
        "x": 0.15,
        "y": 0.05
      },
      "kind": "title",
      "text": "REQORSA MODULATES THE IMMUNE SYSTEM",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "9d67424e-7197-43b6-bdad-f2840886d326",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Audience Definition",
      "slug": "audience-definition",
      "agent": "Storyteller",
      "layer": "slide",
      "matchId": "4f30ef3b-4d64-4b1e-bbb8-e4e2e56ba728",
      "evidence": "The components mention 'humanized mouse model of lung cancer' implying a specific audience or context for the study.",
      "confidence": 0.7
    }
  ],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 20,
      "from": 9,
      "beatId": "727dc990-5781-44c1-9860-17b14bcb030f",
      "arcName": "Monroe's Motivated Sequence",
      "arcSlug": "monroes-sequence",
      "beatName": "Satisfaction",
      "beatSlug": "monroes-sequence-satisfaction",
      "evidence": "Slides 9-20: Solution and traction for REQORSA therapy",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Turn",
      "parentBeatSlug": "turn"
    }
  ],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}