{
  "docId": "019de073-a93c-766f-ab97-ed6e300b196c",
  "docSlug": "203908938c1628b3b3c60bbc024424ae",
  "documentTitle": "Blue Water Vaccines | Results Presentation Deck | 15 slides",
  "authorId": "blue-water-vaccines",
  "authorName": "Blue Water Vaccines",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-10-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 6,
  "pageCount": 15,
  "prevPage": 5,
  "nextPage": 7,
  "slideType": "other",
  "function": "establish_context",
  "density": "balanced",
  "nDataPoints": 0,
  "notes": "The slide describes the mechanism of action for a specific vaccine candidate (BHN97ΔftsY).",
  "elementsJson": null,
  "metadataConfidence": 0.9,
  "imagePath": null,
  "slideHref": "/slides/019de073-a93c-766f-ab97-ed6e300b196c/6",
  "deckHref": "/decks/019de073-a93c-766f-ab97-ed6e300b196c",
  "deckJsonHref": "/decks/019de073-a93c-766f-ab97-ed6e300b196c.json",
  "deckAnchorHref": "/decks/019de073-a93c-766f-ab97-ed6e300b196c#slide-6",
  "components": [
    {
      "bbox": {
        "h": 0.6,
        "w": 0.94,
        "x": 0.03,
        "y": 0.25
      },
      "kind": "list",
      "text": "Noninvasive serotype 19F strain BHN97 which normally causes sinusitis/purulent rhinitis and AOM. Deleted ftsY, a component of the signal recognition particle pathway (SRP) pathway. Vaccine strain BHN97ΔftsY: Attenuated for invasive disease, Deficient for competence/recombination, Surface protein content is similar to the WT, Colonizes murine nasal passages for 3-7 days, Induced serotype-independent immune response.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e33a2f3e-1ca0-458b-a2b3-bcb39888a6db",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.8,
        "x": 0.05,
        "y": 0.93
      },
      "kind": "source-note",
      "text": "Rosch JW, Iverson AR, Humann J, Mann B, Gao G, Vogel P, Mina M, Murrah KA, Perez AC, Edward Swords W, Tuomanen EI, McCullers JA. A live-attenuated pneumococcal vaccine elicits CD4+ T-cell dependent class switching and provides serotype independent protection against acute otitis media. EMBO Mol Med. 2014 Jan;6(1):141-54. doi: 10.1002/emmm.201202150. PMID: 24408968; PMCID: PMC3936495.",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "62aa6f26-b683-428f-b666-7006a4aa7609",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.78,
        "x": 0.11,
        "y": 0.03
      },
      "kind": "title",
      "text": "BWV-201: A Live Attenuated Vaccine Candidate",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "92290ac9-c2de-463d-9d70-45fa824ec3e0",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 6,
      "from": 5,
      "beatId": "60d3e34a-155c-43ef-bb7f-8f98fe851c8f",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Agitate",
      "beatSlug": "problem-agitate-solution-agitate-make-it-worse",
      "evidence": "Slides 5-6 emphasize the need for a more effective solution",
      "position": 1,
      "confidence": 0.8,
      "parentBeatName": "Development",
      "parentBeatSlug": "development"
    },
    {
      "to": 14,
      "from": 6,
      "beatId": "35d1c85f-0b11-4591-bf44-2e9db0903c90",
      "arcName": "Problem-Agitate-Solution",
      "arcSlug": "problem-agitate-solution",
      "beatName": "Solution",
      "beatSlug": "problem-agitate-solution-solution-provide-relief",
      "evidence": "Slides 6-14 present BWV-201 as a potential solution, showcasing its results and potential",
      "position": 2,
      "confidence": 0.8,
      "parentBeatName": "Resolution",
      "parentBeatSlug": "resolution"
    }
  ],
  "loops": [
    {
      "to": 14,
      "from": 6,
      "name": "Jobs To Be Done",
      "slug": "53-jobs-to-be-done",
      "bestFor": "Product innovation, market entry, competitive positioning",
      "matchId": "9cd6c78e-ca73-4c4d-a513-bcdd728807fd",
      "evidence": "Slides 6-14 demonstrate BWV-201's potential to address the needs of pneumococcus vaccine development",
      "position": 1,
      "objective": "Can BWV-201 address the needs of pneumococcus vaccine development?",
      "structure": "The Customer's Job -> Current Solutions (Hired/Fired) -> Unmet Needs -> Our Solution Fit",
      "confidence": 0.8,
      "description": "Reframe the problem around what the customer is trying to accomplish, not what they're buying"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}