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  "documentTitle": "Blue Water Vaccines | Results Presentation Deck | 15 slides",
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  "authorName": "Blue Water Vaccines",
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  "presentationDate": "2022-10-01 00:00:00",
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  "notes": "Uses a before-after-bridge style structure to contrast vaccine efficacy with remaining clinical challenges.",
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      "text": "Microscopic image of pneumococcus bacteria",
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      "text": "Protection is serotype specific; Efficacy was almost exclusive to invasive diseases; Emergence of non-vaccine type; Cost and availability in LMIC; Poor protection against major infections",
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      "text": "Introduction of the highly efficacious polysaccharide-conjugate vaccines (e.g., Prevnar series, Synflorix, etc.) reduced pneumococcus infections dramatically",
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      "text": "Problem: Pneumococcus causes serious diseases (e.g., acute otitis media, sinusitis, pneumonia, bacteremia, sepsis, meningitis, etc that cause high morbidity and mortality in children and elderly",
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      "text": "Moffitt & Malley, 2016",
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      "text": "Pneumococcus Vaccines: Success and Limitations",
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