{
  "docId": "019de073-8778-764b-accb-e5886cb9e840",
  "docSlug": "a27c0c380497fe380fc0ea99c606f1fe",
  "documentTitle": "Equillium | Results Presentation Deck | 32 slides",
  "authorId": "equillium",
  "authorName": "Equillium",
  "documentKindSlug": "conference-presentation",
  "documentKindLabel": "Conference presentation",
  "sourceTypeSlug": "investor_relations",
  "sourceTypeLabel": "Investor relations",
  "presentationDate": "2022-09-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 6,
  "pageCount": 32,
  "prevPage": 5,
  "nextPage": 7,
  "slideType": "key_messages",
  "function": "present_framework",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "The slide includes the KDIGO 2012 CKD prognosis matrix.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de073-8778-764b-accb-e5886cb9e840/6",
  "deckHref": "/decks/019de073-8778-764b-accb-e5886cb9e840",
  "deckJsonHref": "/decks/019de073-8778-764b-accb-e5886cb9e840.json",
  "deckAnchorHref": "/decks/019de073-8778-764b-accb-e5886cb9e840#slide-6",
  "components": [
    {
      "bbox": {
        "h": 0.65,
        "w": 0.45,
        "x": 0.52,
        "y": 0.25
      },
      "kind": "framework",
      "text": "Prognosis of CKD by GFR and Albuminuria Categories: KDIGO 2012",
      "attrs": null,
      "subkind": "instance",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "df5fe47a-42b5-49e9-b8a6-f06eab3ee99a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.65,
        "w": 0.45,
        "x": 0.03,
        "y": 0.22
      },
      "kind": "list",
      "text": "Proteinuria/Albuminuria cause renal damage and fibrosis and are markers of disease activity. Early, rapid and deep reductions in proteinuria minimize kidney damage and are predictive of better renal outcomes. Goal of treatment is to minimize kidney damage and progression to renal failure, preventing the need for renal replacement therapy. Reduction of proteinuria is used by regulatory authorities for approval of new glomerulonephritis therapies, including in lupus nephritis.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "554954df-f5b7-46a0-8ea4-dc3683a6582e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.78,
        "x": 0.11,
        "y": 0.94
      },
      "kind": "source-note",
      "text": "Rovin et al. Kidney International, 2021, Levey et al AJKD, 2020, Rovin et al., The Lancet, 2021; Furie et al., NEJM, 2020; KDIGO (Kidney Disease Improving Global Outcomes) 2012 guidelines CKD evaluation and management",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "660f1c8e-5770-4d3e-93dc-2f1ca6329ada",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.08,
        "w": 0.65,
        "x": 0.03,
        "y": 0.05
      },
      "kind": "title",
      "text": "Proteinuria/Albuminuria: Surrogate Markers for Renal Survival",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "cd627ffc-d96d-4b59-bb3a-eca2239986bb",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Pyramid Principle",
      "slug": "pyramid-principle",
      "agent": "Architect",
      "layer": "slide",
      "matchId": "4e62792d-1e4f-4cf5-b66f-3184ba9afb6e",
      "evidence": "Proteinuria/Albuminuria cause renal damage and fibrosis and are markers of disease activity.",
      "confidence": 0.7
    }
  ],
  "frameworks": [
    {
      "name": "KDIGO-CKD-prognosis-matrix",
      "slug": null,
      "matchId": "b72789c4-ae6d-4a30-9e6f-bdf4980bce8a",
      "evidence": "Standard clinical risk stratification matrix for Chronic Kidney Disease",
      "confidence": 1
    }
  ],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}