{ "docId": "019de073-8778-764b-accb-e5886cb9e840", "docSlug": "a27c0c380497fe380fc0ea99c606f1fe", "documentTitle": "Equillium | Results Presentation Deck | 32 slides", "authorId": "equillium", "authorName": "Equillium", "documentKindSlug": "conference-presentation", "documentKindLabel": "Conference presentation", "sourceTypeSlug": "investor_relations", "sourceTypeLabel": "Investor relations", "presentationDate": "2022-09-01 00:00:00", "orientation": "landscape", "aspectRatio": 1.7777778, "pageNumber": 5, "pageCount": 32, "prevPage": 4, "nextPage": 6, "slideType": "kpi_overview", "function": "size_opportunity", "density": "overcrowded", "nDataPoints": 6, "notes": "The slide uses a list-based layout to present key metrics with corresponding descriptions.", "elementsJson": null, "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019de073-8778-764b-accb-e5886cb9e840/5", "deckHref": "/decks/019de073-8778-764b-accb-e5886cb9e840", "deckJsonHref": "/decks/019de073-8778-764b-accb-e5886cb9e840.json", "deckAnchorHref": "/decks/019de073-8778-764b-accb-e5886cb9e840#slide-5", "components": [ { "bbox": { "h": 0.05, "w": 0.14, "x": 0.17, "y": 0.45 }, "kind": "metric", "text": "10-30%", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "3e0d84b0-66e3-492b-a449-ee1eda6a476a", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.07, "x": 0.24, "y": 0.21 }, "kind": "metric", "text": "50%", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "7a68e245-93fd-49a3-9f53-c91087259825", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.08, "x": 0.23, "y": 0.81 }, "kind": "metric", "text": "60%", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "7fc17bc3-5105-40d3-8228-86f6cf6a6fa1", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.11, "x": 0.2, "y": 0.57 }, "kind": "metric", "text": "< 50%", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "85dee5f4-ef91-49a8-a68a-85b3d4b68d4d", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.14, "x": 0.17, "y": 0.33 }, "kind": "metric", "text": "100,000", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "8877e0fd-2452-4716-bd37-74e345001c75", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.06, "x": 0.25, "y": 0.69 }, "kind": "metric", "text": "2", "attrs": null, "subkind": "big-number", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "aa8aa886-c044-4324-a7cb-29edf3a06584", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.4, "x": 0.41, "y": 0.7 }, "kind": "paragraph", "text": "Approved treatments to improve standard induction therapy", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "263cdfe1-c175-4328-adaa-a696b1f41ae3", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.5, "x": 0.41, "y": 0.21 }, "kind": "paragraph", "text": "Of systemic lupus erythematosus patients will develop lupus nephritis, the most common severe manifestation of the disease", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6bf26c96-abef-4d5e-b8fd-687c5ad6156d", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.5, "x": 0.41, "y": 0.45 }, "kind": "paragraph", "text": "Of patients will progress to end-stage renal disease requiring kidney replacement therapy", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "9002ddd2-067c-4486-b2cd-2b6e66c1f692", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.5, "x": 0.41, "y": 0.57 }, "kind": "paragraph", "text": "Of patients achieve a partial response (> 50% reduction in UPCR) after 6 months on standard of care", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "baed2b77-02f8-4193-b4e9-ac2de9567c55", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.5, "x": 0.41, "y": 0.81 }, "kind": "paragraph", "text": "Of patients fail to achieve a complete response as defined by a UPCR of < 0.5 0.7 g/g at 1 year despite new drug approvals", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "f09c8c7e-6937-40e4-bfad-b0730ec7c4c1", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.3, "x": 0.41, "y": 0.34 }, "kind": "paragraph", "text": "Lupus nephritis patients in the U.S.", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "fca9ca24-185d-47ba-8069-69ae46eef32d", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.6, "x": 0.11, "y": 0.96 }, "kind": "source-note", "text": "Parikh et al., Am J Kid Dis., 2020; Izmirly et al., Arthritis Rheumatol. 2021; Rovin et al., The Lancet, 2021; Furie et al., NEJM, 2020", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "ed56cd0d-370c-4a01-aeec-5735430594bc", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.045, "w": 0.398, "x": 0.037, "y": 0.085 }, "kind": "title", "text": "Lupus Nephritis in Numbers", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "bd713286-7728-4598-a6c4-1e4752fffe66", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [ { "name": "Audience Definition", "slug": "audience-definition", "agent": "Storyteller", "layer": "slide", "matchId": "d65c6fef-5f0f-4bdd-a112-eee948cd7b87", "evidence": "Lupus Nephritis patients in the U.S.", "confidence": 0.7 }, { "name": "Big Idea Formula", "slug": "big-idea-formula", "agent": "Storyteller", "layer": "slide", "matchId": "db8bf8ad-06b7-47ed-895b-b12921c05f07", "evidence": "Of patients fail to achieve a complete response... Of systemic lupus erythematosus patients will develop lupus nephritis...", "confidence": 0.7 } ], "frameworks": [], "arcBeats": [ { "to": 5, "from": 5, "beatId": "517c09ce-88cf-479c-a1b1-84d45103534b", "arcName": "Problem-Agitate-Solution", "arcSlug": "problem-agitate-solution", "beatName": "KPI Overview", "beatSlug": null, "evidence": "The presentation provides an overview of Lupus Nephritis in numbers.", "position": 4, "confidence": 0.8, "parentBeatName": null, "parentBeatSlug": null } ], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }