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      "text": "The CD6-ALCAM pathway modulates T cell activity and trafficking and we believe is central to the pathogenesis of multiple immuno-inflammatory diseases",
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      "text": "CD6 is a co-stimulatory receptor overexpressed on Teff and down-regulated on Treg; CD6High cells exhibit greater pathogenic capacity; Activated leukocyte cell adhesion molecule (ALCAM) is expressed on APCs and tissues; Binding is important for immune synapse, co-stimulation, and trafficking.",
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