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  "notes": "The slide outlines a randomized controlled trial design for Myelofibrosis treatment.",
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      "text": "SVR: ≥35% spleen volume reduction; TSS: ≥50% reduction in total symptom score. SVR powering assumes the response rate is 3% in the P/C treatment arm, 19% in the pacritinib arm. TSS powering assumes the response rate is 14% in the P/C treatment arm and 27% in the pacritinib arm. *Enrollment projections are under evaluation and are likely to change in light of the COVID-19 pandemic and conflict in Europe.",
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      "text": "Study powering (two-sided Type 1 error of 0.05)\nSVR - >99% power to detect at least a 16% difference between the treatment arms\nTSS - >85% power to detect at least a 13% difference between the treatment arms\nData expected mid-2026*",
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