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  "documentTitle": "9 Meters Biopharma | Investor Presentation Deck | 30 slides",
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  "presentationDate": "2022-09-01 00:00:00",
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  "notes": "The slide uses a medical illustration to show the digestive tract and the specific portion of the ileum removed in SBS patients.",
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      "kind": "image",
      "text": "Anatomical diagram of the human digestive system highlighting the liver, stomach, pancreas, and intestines, with a callout indicating the portion of the ileum removed.",
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      "text": "Natural GLP-1 prevents the GI tract from moving rapidly: known as an \"ileal brake\". GLP-1 is naturally produced in a portion of the ileum that is removed during surgical resection.",
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      "text": "Production of natural GLP-1 is compromised in patients with SBS. Portion of the ileum secreting GLP-1 may be removed during resection. Without this brake, there is unregulated gut motility, causing an SBS patient's remaining bowels to empty rapidly and frequently. Inability to absorb nutrients and fluids. Intractable, malabsorptive diarrhea with frequent bowel movements and excessive stool output.",
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      "text": "GLP-2 analogues do not appreciably slow motility to affect rapid GI transit time associated with SBS",
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      "text": "Illustration of one phenotype of SBS with colon-in-continuity; Other phenotypes exist with and without colon-in-continuity",
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