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      "text": "HER2-positive = human epidermal growth factor receptor 2 positive; T-DXd = trastuzumab deruxtecan (Enhertu); DXd = deruxtecan; TOP1i = topoisomerase I inhibition; ADCC = antibody dependent cell-mediated cytotoxicity; DC = dendritic cell; CTL = cytotoxic T lymphocyte; Th1 = T-cell helper 1; NK = natural killer cell; CXCL9, 10 = chemokine (CXC motif) ligand 9 and ligand 10; CCL5 = chemokine (CC motif) ligand 5; IL2 = interleukin 2; IFNs = interferons; IFNγ = interferon gamma; SoC = standard of care; HR+ = hormone-receptor positive; HR- = hormone-receptor negative; IO = immuno-oncology; DDR = DNA damage response.",
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