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  "documentTitle": "23andMe | Investor Presentation Deck | 63 slides",
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  "presentationDate": "2022-02-01 00:00:00",
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  "notes": "Uses a 'fill in the blanks' analogy to explain genotype imputation.",
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      "text": "We type ~650,000 SNPs using our genotyping array, which allows accurate imputation for >35m SNPs in the genome.",
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      "text": "Genotype imputation is much more cost effective than large-scale sequencing. Whole-genome sequencing ~$1000 / sample. Exome sequencing ~$400 / sample. Imputation < $0.01 / sample",
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      "text": "Nearby genetic variants are correlated with each other. Knowing the variant in one position allows nearby variants to be inferred. E.g. Fill in the blanks: The q***k brown f*x jumps ov*r the **zy dog. The same principle applies in genetics. The process of filling in the gaps is known as ‘genotype imputation’.",
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      "text": "The Vast Majority of GWAS Discoveries Can be Made Without Large-scale Sequencing",
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