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      "text": "CSF1R is a receptor expressed on peripheral phagocytic cells and is essential for microglial survival and homeostasis. CSF1 activation of CSF1R pathway requires DAP12 and signals through SYK. Loss-of-function mutations in TREM2/DAP12 or CSF1R lead to similar devastating neurodegenerative diseases. Both TREM2 and CSF1R signaling converge on DAP12/SYK.",
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      "text": "Otero et al, Nat Immunol 2009; Oosterhof et al., 2018; Konishi and Kiyama, Front. Cell. Neurosci 2018; Schlepckow et al, EMBO Mol Med 2020; Lee et al, Bone Research 2021",
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