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      "text": "Conclusion: Caffeine-based excipient proven in externally validated, rigorous scientific evaluation to achieve all desired target parameters for a viable SQ formulation",
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      "text": "Caffeine-containing formulations met target stability requirements for a viable drug product",
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      "text": "Use of caffeine-based excipient to reduce viscosity demonstrated for two mAbs, ipilimumab (Yervoy) and infliximab (Remicade). Ipilimumab: caffeine reduced viscosity from 45-78% in three buffers. Infliximab: caffeine reduced viscosity by 77% vs. control.",
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      "text": "Source: “Caffeine as a viscosity reducer for highly concentrated monoclonal antibody solutions”, Journal of Pharmaceutical Sciences, 110 (2021) 3594–3604, https://doi.org/10.1016/j.xphs.2021.06.030",
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