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  "documentTitle": "23andMe | Investor Day Presentation Deck | 78 slides",
  "authorId": "23andme",
  "authorName": "23andMe",
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  "presentationDate": "2022-01-01 00:00:00",
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  "notes": "The slide uses a before-after visual to illustrate the mechanism of action.",
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      "kind": "image",
      "text": "23ME'610 Activates T-cell Function by Blocking the CD200R1 Checkpoint",
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      "text": "23ME '610 is a fully humanized, effectorless, IgG1 antibody against human CD200R1\n23ME '610 binds CD200R1 with high affinity (KD < 0.1 nM)\n23ME '610 blocks CD200 ligand binding to CD200R1, resulting in inhibition of immunosuppressive signaling\nThe restoration of T-cell activity by 23ME '610 was demonstrated using in vitro models of the tumor microenvironment\nNo adverse effects of blocking CD200R1 have been observed in nonclinical toxicology studies",
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      "kind": "title",
      "text": "23ME-00610 (23ME'610) Binds with High Affinity to CD200R1 and Inhibits Immunosuppressive Signaling",
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      "bestFor": "Transformation planning, 100-day plans, resource allocation",
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      "evidence": "The presentation deck presents data and research findings on 23ME-00610, a novel immuno-oncology antibody targeting CD200R1",
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      "objective": "Can 23andMe's immuno-oncology antibody targeting CD200R1 provide a quick win in cancer treatment?",
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