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  "documentTitle": "23andMe | Investor Day Presentation Deck | 78 slides",
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  "authorName": "23andMe",
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  "presentationDate": "2022-01-01 00:00:00",
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  "notes": "The slide uses a biological pathway diagram to illustrate the mechanism of action.",
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      "kind": "image",
      "text": "CD200:CD200R1 Signaling pathway diagram",
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      "text": "CD200R1 is an inhibitory receptor expressed on T-cells and myeloid cells\nCD200 is the only known ligand for CD200R1 in humans and is highly expressed in certain cancers\nBinding of CD200 to C200R1 decreases the ability of T-cells to recognize and kill cancer cells\nSeveral viruses, including HHV8 have co-opted CD200 analogues to suppress and evade the host immune response",
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      "text": "References: J Virol 2012;86:6246, J Virol 2004;78:7667, J Immunol 2005;175:4441, Structure 2013;21:820, JCI Insight 2018;3:e96836",
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      "text": "CD200R1 is an Immune Checkpoint",
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      "name": "Quick Win Big Bet",
      "slug": "47-quick-win-big-bet",
      "bestFor": "Transformation planning, 100-day plans, resource allocation",
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      "evidence": "The presentation deck presents data and research findings on 23ME-00610, a novel immuno-oncology antibody targeting CD200R1",
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      "objective": "Can 23andMe's immuno-oncology antibody targeting CD200R1 provide a quick win in cancer treatment?",
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