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  "documentTitle": "Kymera | Investor Day Presentation Deck | 105 slides",
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  "notes": "Shows that KT-253 (degrader) induces apoptosis even after short exposure, whereas DS-3032 (SMI) does not.",
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      "text": "4 hr target coverage by KT-253 is sufficient to induce apoptosis in contrast to SMIs; Supports hypothesis that intermittent dosing schedule of KT-253 can drive efficacy while increasing therapeutic index",
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      "text": "Short Term Exposure to MDM2 Degrader, but not SMI, is Sufficient to Commit Cells to Undergo Apoptosis",
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