{
  "docId": "019de071-dcb4-71ce-82aa-3fde96763369",
  "docSlug": "c85401f3daf1ffc5cb0e20a3335252d7",
  "documentTitle": "BenevolentAI | SPAC Presentation Deck | 42 slides",
  "authorId": "benevolentai",
  "authorName": "BenevolentAI",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investment_bank",
  "sourceTypeLabel": "Investment bank",
  "presentationDate": "2021-12-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7777778,
  "pageNumber": 23,
  "pageCount": 42,
  "prevPage": 22,
  "nextPage": 24,
  "slideType": "solution",
  "function": "present_solution",
  "density": "dense",
  "nDataPoints": 3,
  "notes": "Includes technical data on IC50, cytokine inhibition (TNFa, IL-4), and CGRP inhibition in DRG neurons.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de071-dcb4-71ce-82aa-3fde96763369/23",
  "deckHref": "/decks/019de071-dcb4-71ce-82aa-3fde96763369",
  "deckJsonHref": "/decks/019de071-dcb4-71ce-82aa-3fde96763369.json",
  "deckAnchorHref": "/decks/019de071-dcb4-71ce-82aa-3fde96763369#slide-23",
  "components": [
    {
      "bbox": {
        "h": 0.3,
        "w": 0.3,
        "x": 0.55,
        "y": 0.6
      },
      "kind": "chart",
      "text": "BEN-2293 mediated inhibition of CGRP in DRG neurons",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "34637905-7dd5-4eb6-a7d3-e92275408653",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.4,
        "x": 0.55,
        "y": 0.25
      },
      "kind": "chart",
      "text": "BEN-2293 Inhibition of human primary T-cell activation (TNFa and IL-4)",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d389475c-63a5-4b28-be90-1f5f2004d95c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.6,
        "w": 0.45,
        "x": 0.05,
        "y": 0.25
      },
      "kind": "list",
      "text": "BEN-2293 is highly selective for Trk receptors; dose dependently inhibits release of inflammatory Th1 and Th2 cytokines; inhibits release of CGRP; demonstrates excellent tolerability.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "2776b49f-5477-4d0a-989f-66108fb3b305",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.1,
        "w": 0.4,
        "x": 0.05,
        "y": 0.9
      },
      "kind": "source-note",
      "text": "Key: Tropomyosin-related kinase (Trk) receptor tyrosine kinase family, namely TrkA, TrkB, and TrkC; Nerve Growth Factor (NGF); Brain Derived Neurotrophic Factor (BDNF); Neurotrophin-3 (NTF-3)/NT3",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "85578a02-1350-42c0-bf63-a9d0ce08996c",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.15,
        "w": 0.9,
        "x": 0.05,
        "y": 0.05
      },
      "kind": "title",
      "text": "BEN-2293 is expected to provide both symptomatic relief and to reverse disease progression in atopic dermatitis",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "7a1b15aa-9048-40e5-93e8-48ce789a874f",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "AIDA Model",
      "slug": "aida-model",
      "agent": "Storyteller",
      "layer": "slide",
      "matchId": "537593de-4136-4b4e-8b87-89d0209c3658",
      "evidence": "The slide presents a solution with multiple benefits, including symptomatic relief and disease progression reversal, which aligns with the AIDA model's attention, interest, desire, and action components.",
      "confidence": 0.7
    }
  ],
  "frameworks": [],
  "arcBeats": [],
  "loops": [
    {
      "to": 24,
      "from": 21,
      "name": "Quick Win Big Bet",
      "slug": "47-quick-win-big-bet",
      "bestFor": "Transformation planning, 100-day plans, resource allocation",
      "matchId": "1f7e984e-ea28-4a79-851c-c2fb54c3288f",
      "evidence": "The deck presents BenevolentAI's portfolio and progress",
      "position": 1,
      "objective": "Showcase quick wins and big bets in BenevolentAI's portfolio",
      "structure": "The Full List -> Quick Wins (Low effort, High impact) -> Big Bets (High effort, High impact) -> Sequenced Roadmap",
      "confidence": 0.6,
      "description": "Separate initiatives into immediate wins and longer-term strategic bets"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}