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  "documentTitle": "Chimerix | Investor Conference Presentation Deck | 32 slides",
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  "presentationDate": "2021-11-01 00:00:00",
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  "notes": "Includes a diagram of brain regions and a dot plot showing patient age distribution across different midline sites.",
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      "text": "Dot plot of patient age vs midline site",
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      "text": "Brain anatomy diagram showing K27M and G34V/R locations",
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      "text": "H3 K27M is detected in 50-90% of midline gliomas\nMore prevalent in pediatric populations but also prevalent adults as well\nHighly aggressive malignancy; invariably lethal\nNo effective drug therapies to date for recurrence\nNo definite objective responses to systemic therapies by RANO HGG reported in literature in the recurrent setting",
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      "text": "Lulla et al., Science Advances, 2016; Solomon et al., Brain Pathology 26 (2016) 569–580",
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      "text": "Diffuse Midline Glioma, H3 K27M-mutant",
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