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  "documentTitle": "Chimerix | Investor Conference Presentation Deck | 32 slides",
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  "presentationDate": "2021-11-01 00:00:00",
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  "notes": "The slide includes specific clinical definitions for response categories and footnotes explaining patient exclusions and criteria.",
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      "text": "30.0% (95% CI: 17.9 - 44.6%) achieved an objective response by RANO-HGG and/or RANO-LGG criteria",
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      "text": "1Integrated RANO LGG criteria assessment by dual reader BICR 2Eight overall radiographic SD accompanied by increase in corticosteroids; 3 overall radiographic PD accompanied by decrease in corticosteroids 3Three patients did not have on-treatment monotherapy MRIs available for BICR; one patient censored prior to first on-treatment MRI",
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      "text": "RANO-LGG N=50 ORR (CR + PR + MR) 13 (26%) 95% CI: 15 – 40% Complete Response (CR) 0 (0%) Partial Response (PR) 6 (12%) Minor Response (MR) 7 (14%) Stable Disease (SD) 8 (16%) Not Evaluable (NE) 11 (22%) Progressive Disease (PD) 14 (28%) Not Applicable (NA) 4 (8%) Disease Control Rate (CR + PR + MR + SD) 21 (42%) 95% CI: 28 – 57%",
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