{
  "docId": "019de071-805e-75da-a9c3-e9573cb6e94f",
  "docSlug": "f179c2894ff7ef65a3c6d24dd4bec442",
  "documentTitle": "Exscientia | IPO Presentation Deck | 60 slides",
  "authorId": "exscientia",
  "authorName": "Exscientia",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investment_bank",
  "sourceTypeLabel": "Investment bank",
  "presentationDate": "2021-09-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7893755,
  "pageNumber": 42,
  "pageCount": 60,
  "prevPage": 41,
  "nextPage": 43,
  "slideType": "other",
  "function": "illustrate_case",
  "density": "dense",
  "nDataPoints": 2,
  "notes": "The slide uses a process-flow layout to show the progression from experiment to AI-driven design to final compound.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de071-805e-75da-a9c3-e9573cb6e94f/42",
  "deckHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f",
  "deckJsonHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f.json",
  "deckAnchorHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f#slide-42",
  "components": [
    {
      "bbox": {
        "h": 0.3,
        "w": 0.9,
        "x": 0.05,
        "y": 0.25
      },
      "kind": "diagram",
      "text": "Experiment -> AI solutions -> Best-in-class compound",
      "attrs": null,
      "subkind": "process",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "2e850297-ad40-427a-8529-52656ab17953",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.2,
        "w": 0.28,
        "x": 0.36,
        "y": 0.55
      },
      "kind": "list",
      "text": "2D evolutions from fragments drove delivery of novel, potent molecules. Knowledge from published crystal structures informed 3D generative design and enhanced potency and selectivity",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "54857c54-ccc1-4fd1-a53d-bf37a66ccb02",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.2,
        "w": 0.28,
        "x": 0.05,
        "y": 0.55
      },
      "kind": "list",
      "text": "Seed data. SPR fragment screen delivered novel chemical equity. Selectivity. Suite of adenosine receptor assays developed in multiple species",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "83fcc46e-2e3e-4d8f-ae34-573ed7e720c4",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.2,
        "w": 0.28,
        "x": 0.68,
        "y": 0.55
      },
      "kind": "list",
      "text": "Development candidate designed in <9 months and was 163rd novel compound prepared. Tight control of physical properties provided high oral absorption whilst limiting CNS exposures. Delivered efficient, well balanced molecule (<350 MW)",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "a5adf243-05aa-48d7-a724-6473fe97fcac",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.5,
        "x": 0.03,
        "y": 0.12
      },
      "kind": "title",
      "text": "Proprietary fragment data coupled with 2D and 3D evolutions",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "795eb27e-04c6-459a-85f2-68d7abbeee90",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.6,
        "x": 0.03,
        "y": 0.06
      },
      "kind": "title",
      "text": "Case study: A2aR antagonist – integration of biophysics and AI",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "63e9d14b-c0ba-4507-985e-1ae728107370",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Logical chain",
      "slug": "logical-chain",
      "agent": null,
      "layer": "slide",
      "matchId": "42a9e804-0a0b-4284-b670-afa64c131bc9",
      "evidence": "Development candidate designed in <9 months and was 163rd novel compound prepared. Tight control of physical properties provided high oral absorption whilst limiting CNS exposures.",
      "confidence": 0.7
    }
  ],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 60,
      "from": 4,
      "beatId": "5dda98c6-c560-4b21-aa1c-95b617a27a20",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Solution",
      "beatSlug": "sequoia-pitch-solution",
      "evidence": "The deck presents a comprehensive solution throughout pages 4-60.",
      "position": 1,
      "confidence": 0.8,
      "parentBeatName": "Turn",
      "parentBeatSlug": "turn"
    }
  ],
  "loops": [
    {
      "to": 60,
      "from": 4,
      "name": "Golden Circle",
      "slug": "11-golden-circle",
      "bestFor": "Visionary leadership, brand positioning, mission statements",
      "matchId": "3b6b60bf-18b7-4458-bffa-eba1b1ca0583",
      "evidence": "The deck presents a comprehensive loop on the golden circle of problem-solution-benefit.",
      "position": 1,
      "objective": "Explain how Exscientia's AI-driven platform can solve the problem of inefficient drug discovery.",
      "structure": "The Why (Belief) -> The How (Process) -> The What (Result)",
      "confidence": 0.7,
      "description": "Invert the typical pitch by starting with why you exist, rather than what you do"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}