{
  "docId": "019de071-805e-75da-a9c3-e9573cb6e94f",
  "docSlug": "f179c2894ff7ef65a3c6d24dd4bec442",
  "documentTitle": "Exscientia | IPO Presentation Deck | 60 slides",
  "authorId": "exscientia",
  "authorName": "Exscientia",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investment_bank",
  "sourceTypeLabel": "Investment bank",
  "presentationDate": "2021-09-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7893755,
  "pageNumber": 31,
  "pageCount": 60,
  "prevPage": 30,
  "nextPage": 32,
  "slideType": "competitive_analysis",
  "function": "compare_peers",
  "density": "dense",
  "nDataPoints": 18,
  "notes": "The slide uses a series of small-multiple line charts to demonstrate dose-response curves across different time points (24h, 48h, 72h).",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de071-805e-75da-a9c3-e9573cb6e94f/31",
  "deckHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f",
  "deckJsonHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f.json",
  "deckAnchorHref": "/decks/019de071-805e-75da-a9c3-e9573cb6e94f#slide-31",
  "components": [
    {
      "bbox": {
        "h": 0.5,
        "w": 0.24,
        "x": 0.74,
        "y": 0.22
      },
      "kind": "callout",
      "text": "Key results: (A) EXS617 has same depth of response on ovarian cancer cells as CDK4/6 inhibitors but at lower concentrations (N=10). (B) The CDK4/6 inhibitors have greater immune cell (off-target) effects than EXS617.",
      "attrs": null,
      "subkind": "primary",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "8afe6932-91fd-481e-be24-d48fbb5012bc",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.65,
        "w": 0.32,
        "x": 0.36,
        "y": 0.235
      },
      "kind": "chart",
      "text": "Viable Cancer and Immune Cells",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "42dadd00-94e8-4433-9043-b1b3e6e430d6",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.65,
        "w": 0.32,
        "x": 0.04,
        "y": 0.235
      },
      "kind": "chart",
      "text": "Ovarian Cancer Cell Fraction",
      "attrs": null,
      "subkind": "line",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "5f5db8f2-98d8-4431-949f-0779cc8e1fac",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.05,
        "w": 0.65,
        "x": 0.26,
        "y": 0.93
      },
      "kind": "source-note",
      "text": "Shaded areas show interquartile range of estimated EC50 values across samples, at each drug and time point. Asterisks indicate significance of treatment vs. media difference in log-averages (t-test): <0.001=***, <0.01=**, <0.05=*. A and B) N=10 samples. TME = tumour microenvironment",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c14e7eea-7741-469b-a700-9517c5910ee6",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.04,
        "w": 0.8,
        "x": 0.04,
        "y": 0.12
      },
      "kind": "title",
      "text": "TME evaluation from patient samples shows impact beyond just cancer cells",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "6c7530b8-d0f6-4094-96af-d32a5418a235",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.92,
        "x": 0.04,
        "y": 0.05
      },
      "kind": "title",
      "text": "CDK7i: Sparing immune cells in comparison to CDK4/6i",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "836330a9-06a2-4c60-b541-9e186009a573",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Chart Selection Guide",
      "slug": "chart-selection-guide",
      "agent": "Designer",
      "layer": "slide",
      "matchId": "1ceea53d-1219-411a-9de7-b251b4cba1b5",
      "evidence": "chart/line: Viable Cancer and Immune Cells",
      "confidence": 0.6
    }
  ],
  "frameworks": [],
  "arcBeats": [
    {
      "to": 60,
      "from": 4,
      "beatId": "5dda98c6-c560-4b21-aa1c-95b617a27a20",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Solution",
      "beatSlug": "sequoia-pitch-solution",
      "evidence": "The deck presents a comprehensive solution throughout pages 4-60.",
      "position": 1,
      "confidence": 0.8,
      "parentBeatName": "Turn",
      "parentBeatSlug": "turn"
    },
    {
      "to": 32,
      "from": 28,
      "beatId": "364bb9c2-365f-49cf-9e48-6bd24128bcdc",
      "arcName": "The Sequoia Pitch",
      "arcSlug": "sequoia-pitch",
      "beatName": "Competition",
      "beatSlug": "sequoia-pitch-competition",
      "evidence": "The deck discusses competition on pages 28-32.",
      "position": 3,
      "confidence": 0.8,
      "parentBeatName": "Evidence",
      "parentBeatSlug": "evidence"
    }
  ],
  "loops": [
    {
      "to": 60,
      "from": 4,
      "name": "Golden Circle",
      "slug": "11-golden-circle",
      "bestFor": "Visionary leadership, brand positioning, mission statements",
      "matchId": "3b6b60bf-18b7-4458-bffa-eba1b1ca0583",
      "evidence": "The deck presents a comprehensive loop on the golden circle of problem-solution-benefit.",
      "position": 1,
      "objective": "Explain how Exscientia's AI-driven platform can solve the problem of inefficient drug discovery.",
      "structure": "The Why (Belief) -> The How (Process) -> The What (Result)",
      "confidence": 0.7,
      "description": "Invert the typical pitch by starting with why you exist, rather than what you do"
    }
  ],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}