{
  "docId": "019de071-4e1f-74a8-b040-3577ed32c01f",
  "docSlug": "716a1960d23114ac9a8076dbc94bca80",
  "documentTitle": "Tenaya Therapeutics | IPO Presentation Deck | 36 slides",
  "authorId": "tenaya-therapeutics",
  "authorName": "Tenaya Therapeutics",
  "documentKindSlug": "pitchdeck",
  "documentKindLabel": "Pitch deck",
  "sourceTypeSlug": "investment_bank",
  "sourceTypeLabel": "Investment bank",
  "presentationDate": "2021-07-01 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.7843866,
  "pageNumber": 21,
  "pageCount": 36,
  "prevPage": 20,
  "nextPage": 22,
  "slideType": "solution",
  "function": "present_solution",
  "density": "dense",
  "nDataPoints": 2,
  "notes": "Includes anatomical pathology image and molecular structure diagram of desmosomes.",
  "elementsJson": null,
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019de071-4e1f-74a8-b040-3577ed32c01f/21",
  "deckHref": "/decks/019de071-4e1f-74a8-b040-3577ed32c01f",
  "deckJsonHref": "/decks/019de071-4e1f-74a8-b040-3577ed32c01f.json",
  "deckAnchorHref": "/decks/019de071-4e1f-74a8-b040-3577ed32c01f#slide-21",
  "components": [
    {
      "bbox": {
        "h": 0.35,
        "w": 0.45,
        "x": 0.52,
        "y": 0.55
      },
      "kind": "image",
      "text": "Diagrams of desmosomes and gap junctions",
      "attrs": null,
      "subkind": "infographic",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "11f34678-7db0-4a54-9de0-b4513e71157f",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.45,
        "w": 0.25,
        "x": 0.03,
        "y": 0.25
      },
      "kind": "image",
      "text": "Pathology of heart showing RV dilation and fibrosis",
      "attrs": null,
      "subkind": "photo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "7c3aecf8-71c8-465c-8e6b-eb8991bab1ce",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.6,
        "w": 0.22,
        "x": 0.28,
        "y": 0.25
      },
      "kind": "list",
      "text": "Pathophysiology: Mutations in PKP2 involve desmosomes; Fibrofatty muscle replacement. Disease Symptoms: Young adulthood onset, arrhythmias, cardiac arrest. Standard of Care: No treatments address underlying genetic cause.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e81703a0-3376-4e1d-b8d8-cb3f6c380cf6",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.45,
        "x": 0.52,
        "y": 0.25
      },
      "kind": "table",
      "text": "Target Cell: Cardiomyocyte; Modality: AAV; Gene: PKP2; MOA: Lock and key; Stage: Candidate selection",
      "attrs": null,
      "subkind": "kpi",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "70565109-d436-49ef-b068-11f9f9fe6208",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.95,
        "x": 0.03,
        "y": 0.1
      },
      "kind": "title",
      "text": "Addressing the Leading Genetic Cause of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Affecting >70K Patients in the US Alone",
      "attrs": null,
      "subkind": "action-title",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "af4f1d53-ca1a-4842-92f0-ee8c30c558e0",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.06,
        "w": 0.45,
        "x": 0.03,
        "y": 0.03
      },
      "kind": "title",
      "text": "PKP2 Gene Therapy Program",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "9c7826dd-9f9d-4d1d-9819-dd498e5a0b6a",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [
    {
      "name": "Problem Statement Canvas",
      "slug": "problem-statement-canvas",
      "agent": "Architect",
      "layer": "slide",
      "matchId": "8b6f20c8-b070-4e93-9e0f-1971334a1d52",
      "evidence": "Pathophysiology: Mutations in PKP2 involve desmosomes; Fibrofatty muscle replacement. Disease Symptoms: Young adulthood onset, arrhythmias, cardiac arrest.",
      "confidence": 0.6
    }
  ],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}