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  "notes": "The chart uses a logarithmic scale to show fold-selectivity. NVL-655 shows significantly higher selectivity for ALK variants compared to the other two drugs.",
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      "text": "pTRKB IC50 values for brigatinib, ceritinib, and alectinib were not reached at the highest dose tested (10 µM, n=1), and therefore relative selectivity versus ALK variants was not calculated.",
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      "text": "Pelish, H.E., Tangpeerachaikul, A., Kohl, N.E., Shair, M.D., Porter, J.R., and Horan, J.C. AACR Conference 2021; Corrected and additional data on file",
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      "text": "Potential for Differentiation vs CNS Active ALK Inhibitor Lorlatinib",
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