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  "documentTitle": "Erasca | IPO Presentation Deck | 46 slides",
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  "authorName": "Erasca",
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  "presentationDate": "2021-07-01 00:00:00",
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  "notes": "The slide uses a line chart to show drug concentration over time and a table to summarize key PK/PD metrics (Cmax, Cmin, T>IC90, T<IC50).",
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      "text": "Goal is to maximize the time above IC90 to improve cancer cell killing, while maintaining Cmin near or below IC50 to give normal cells a treatment break (i.e., extend time below IC50)",
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      "text": "Phase 1 PK data showed QW is preferable to QD dosing; simulations suggest BID-QW dosing may improve PK/PD profiles and combinability even more",
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