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  "documentTitle": "AbCellera | IPO Presentation Deck | 38 slides",
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  "authorName": "AbCellera",
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  "presentationDate": "2020-12-01 00:00:00",
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  "pageNumber": 33,
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  "notes": "The slide highlights the engineering process (step 5 of the process flow) to ensure stable pairing of heavy and light chains.",
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      "kind": "diagram",
      "text": "SOURCE SEARCH FIND ANALYZE ENGINEER",
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      "text": "Diagram showing two parental IgG antibodies combining into a bispecific IgG",
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      "text": "3 protein-protein interfaces with 1 to 4 mutations per domain to ensure correct and stable pairing of multiple heavy (VH CH) and light (VL CL) chains",
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      "text": "Example mutations at a heavy-light chain (Fab) interface:",
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      "kind": "title",
      "text": "COMBINE ANY TWO ANTIBODIES TO CREATE NATIVE BISPECIFICS.",
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