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  "notes": "Data shows fold change from baseline for four different markers, comparing lower vs higher doses with statistical significance (p-values) indicated.",
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      "text": "D: Proliferating (Ki67+) effector memory CD8 T cells",
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      "text": "Pharmacological activity was observed across a broad range of dose levels\nIncreased levels of peripheral IFN-g and IP-10, increased frequency of proliferating (Ki67+) total CD8 and effector memory CD8+ T cells were observed",
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      "text": "Data extraction: June 26, 2020. Maximal fold-change from baseline measured during cycle 1. Lower doses correspond to dose levels ≤200 mg and higher doses correspond to dose levels ≥400 mg. Wilcoxon-Mann-Whitney test. IFN, interferon; IP-10, interferon-gamma-inducible protein 10.",
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      "text": "BNT311: Phase 1 / 2a - Pharmacodynamics",
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