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      "text": "Symptoms of PWS include neonatal hypotonia followed by hyperphagia and excessive weight gain that begins around 5-8 years of age and lasts until death. Hyperphagia leads to severe obesity, metabolic disorder, and is a leading cause of morbidity and mortality. Intellectual disability and developmental delay and psychiatric disorders are also common. The average age of death is approximately 30 years. The estimated prevalence of PWS is 40,000 patients in the US and EU.",
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