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  "documentTitle": "Taysha | IPO Presentation Deck | 66 slides",
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  "authorName": "Taysha Gene Therapies",
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  "notes": "Includes a citation for disease reversibility research.",
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      "text": "Stage I: 6-18 months, Stage II: 1-4 years, Stage III: 4-10 years, Stage IV: >10 years",
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      "text": "Rett Syndrome is caused by mutations in the X-linked MECP2 gene; MeCP2 regulates the expression of many genes involved in normal brain function; A brief period of normal development is followed by a devastating loss of speech and purposeful hand use along with the emergence breathing abnormalities; Disease reversibility described in animal models as demonstrated by Sir Adrian Bird; The estimated prevalence of Rett syndrome is 25,000 patients in the US and EU",
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      "text": "1. Guy J et al. Science 2007",
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      "text": "Rett syndrome is one of the most common genetic causes of intellectual disabilities in women",
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