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  "documentTitle": "Kymera | IPO Presentation Deck | 49 slides",
  "authorId": "kymera",
  "authorName": "Kymera",
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  "presentationDate": "2020-08-01 00:00:00",
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  "notes": "The slide uses volcano plots to show that STAT3 is the only protein significantly degraded, while other STAT family members remain unaffected.",
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      "text": "Volcano plots showing protein level fold change vs p-value for hPBMCs and SU-DHL-1 cells.",
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      "text": "STAT Family Members: STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6",
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      "text": "Deep mass spectrometry-based proteomics to assess STAT3 specificity performed. hPBMC and tumor cells (SU-DHL-1) treated with Kymera's STAT3 degrader. STAT3 was the only protein to be degraded with statistical significance. Data demonstrate highly selective degradation profile.",
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