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      "text": "PC14586 Induces Transcription of p21 and MDM2 Selectively in Cell Lines with the p53 Y220C Mutation",
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      "text": "In an ideal scenario, everything but the Y220C (dark blue line) should appear as a flat line along the x-axis... We do not see why this would occur if PC14586 is designed to only bind to the crevice found in Y220C mutations.",
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      "text": "PMV claims that PC14586 only binds to the crevice created by the Y220C mutation. None of the other tested p53 hotspot mutations... should be affected.",
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      "text": "9 PMV, 10-K, 12, 3/1/2022\n10 PMV, 10-K, 12, 3/1/2022",
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      "text": "PMV's Preclinical Laboratory Results Indicate Their Lead Candidate Is Likely to Have Serious Side Effects",
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