{ "docId": "019dd923-622c-750b-8b9a-4b91788fc785", "docSlug": "5fadb686cc03", "documentTitle": "Twist Bioscience (TWST)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2022-11-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.2941177, "pageNumber": 76, "pageCount": 236, "prevPage": 75, "nextPage": 77, "slideType": "expose_contradiction", "function": "expose_contradiction", "density": "dense", "nDataPoints": 0, "notes": "The slide uses a Q&A transcript format to undermine the company's claims of automation.", "elementsJson": [ "paragraph", "quote_block", "footnote" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-4b91788fc785/76", "deckHref": "/decks/019dd923-622c-750b-8b9a-4b91788fc785", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-4b91788fc785.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-4b91788fc785#slide-76", "components": [ { "bbox": null, "kind": "callout", "text": "Imagine 16 people with their own [liquid handling] robots.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-0932-77cf-bfea-0ac1e50a6192", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.05, "w": 0.9, "x": 0.05, "y": 0.35 }, "kind": "paragraph", "text": "“Chip” requires teams of humans doing “manual labor” “over and over” to fill up chamber, with the assistance of widely-used liquid handling machines, across a number of different laboratories; takes 12-16 humans a day", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "04237733-5471-441a-96fc-da56365831b6", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.5, "w": 0.9, "x": 0.05, "y": 0.4 }, "kind": "quote", "text": "A: “But basically, we make tiny pools of DNA base pairs, and then we discretely pool them together with the help of automated liquid handlers. So, we do these things called rolling circle amplification and preliminary cycling assembly.”\nQ: “How much manual labor is involved in that order? When you say automated liquid handling machines, you probably need a lab technician on that stuff. How does it work?”\nA: “Correct. So, you can imagine every automated liquid handling machine has sort of like a robotic person that will do these, and they are operational 24 hours a day. Every hour, every minute, every day, the operations are continuing, and orders are being filled. So, manual labor, yeah, split between about three or four different laboratories, inside of Twist.”\nQ: “Is it an automated liquid handling machine that’s basically filling up each of those plates?”\nA: “Yeah, it’s a combination of many automated liquid handlers being directed by humans and then plates being transferred from one lab into another lab.”\nQ: “How many humans does it take to fill all 96,000 of those chambers? How long does it take?”\nA: “Less than a day.”\nQ: “Does it take one person working all day to fill up all 96,000 of those wells in that chip or more than one person?”\nA: “Imagine 16 people with their own robots, and the robot is what’s handling the sample, and the person is just putting the plates on there and pressing buttons.”\nQ: “But how many times do they need to repeat that to fill up the whole plate?”\nA: “Each person is directed into their own job, into their own robot. And when they come in, they will work a 12-hour shift and do the same process over and over.”\nQ: “So, it takes 12 people to fill up all of the little holes in that 96,000 miniaturized well plate, and that takes about how many hours total for all 12 of those people?”\nA: “Assisted by robots, yes. Less than 12 hours.” -Ex-Twist employee in manufacturing, now a research professor", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6a632244-f2be-4754-a062-b8777c99a535", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "Imagine 16 people with their own robots, and the robot is what’s handling the sample, and the person is just putting the plates on there and pressing buttons. — Ex-Twist employee in manufacturing, now a research professor", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-0932-77cf-bfea-0ce5b5e33538", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.3, "x": 0.05, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "a21906a8-9866-4f9b-9eee-e3db14df4b18", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.25, "w": 0.9, "x": 0.05, "y": 0.08 }, "kind": "title", "text": "Another ex-employee, who worked in a manufacturing role, detailed the chip’s dependence on manual labor, stating that it required “humans” working 12-hour shifts around the clock – “manual labor, yeah” – operating liquid handling machines “over and over” and moving plates: “Imagine 16 people with their own [liquid handling] robots.” He stated that it took about a dozen people an entire day just to fill up the chip’s chambers.", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "35163afe-fa8a-47a0-9155-4243fdb91d60", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "fraud-exposure", "slug": null, "matchId": "2383e96c-950f-4bcb-a6aa-b89c2d5f221b", "evidence": "The slide uses expert testimony to contradict company claims of automation.", "confidence": 0.9 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }