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      "text": "Twist’s losses indicate identical struggles to those that doomed other companies that used the same Agilent “chip” as the foundation of their manufacturing.",
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      "text": "An ex-Agilent oligonucleotide manufacturing expert who noted that Twist’s platform is “basically the same as Agilent’s technology,” stated that DNA synthesis on the chip is extremely expensive given costly reagents and enzymes and that errors “go up geometrically” as sequences get longer: “the detection of those errors gets more costly and more expensive.” An ex-Twist employee in a senior role corroborated that “the enzymes are not cheap, and the sequencing reagents are not cheap, and it takes a lot of time.”",
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      "text": "Chip-based synthesis is extremely expensive given costly reagents and enzymes; “pretty complex”; cost and errors “go up geometrically” as sequences get longer; Twist has same problems because “same as Agilent” “It’s based on the processing of rather sophisticated molecular biology science. The number and type of reagents are critical in their manufacturing process, and these are expensive as well... when you go up that high in the number of bases in your gene sequence, the errors go up geometrically, and the detection of those errors gets more costly and more expensive... which in Twist’s case is basically the same as Agilent’s technology.” - Longtime oligonucleotide manufacturing expert and executive; ex-Agilent",
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      "text": "Twist’s manufacturing inputs like enzymes and reagents “are not cheap” Q: “What are the other costs? “ A: “Molecular biology downstream. Enzymes for assembly, enzymes for cloning, and then sequencing. You provide sequence-verified clones...the enzymes are not cheap, and the sequencing reagents are not cheap, and it takes a lot of time.” - Ex-employee in senior product management and sales leadership roles",
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      "text": "“basically the same as Agilent’s technology,” stated that DNA synthesis on the chip is extremely expensive given costly reagents and enzymes and that errors “go up geometrically” as sequences get longer: “the detection of those errors gets more costly and more expensive.” — Longtime oligonucleotide manufacturing expert and executive; ex-Agilent. “the enzymes are not cheap, and the sequencing reagents are not cheap, and it takes a lot of time.” — Ex-employee in senior product management and sales leadership roles",
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