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  "documentTitle": "TransMedics (TMDX)",
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  "presentationDate": "2025-01-10 00:00:00",
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  "notes": "The slide uses a direct quote from a surgeon to undermine the credibility and clinical utility of the TransMedics OCS device.",
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      "text": "there are concerns with pumping a heart for a long period...a pump is not a benign thing...if you go back and read the comments on the FDA panel, there’s data from TransMedics studies that suggest myocardial edema...whether the data will ultimately support this is still being hotly debated at transplant meetings...there still remains skepticism about pumping organs...and increasing the ischemic time...the data that surrounds OCS, does the patient really benefit, and is there truly no hard done to that organ?",
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      "text": "A cardiac surgeon at a major Midwest center – who was on the FDA panel that voted to approve TransMedics device – now barely uses the heart pump, in ~6 out of 60 total transplants per year. He stated the pump is controversial and still “hotly debated” years after FDA approval, with no proven benefit for lung or heart, and that it may in fact injure the heart – “there are concerns with pumping a heart for a long period...a pump is not a benign thing...if you go back and read the comments on the FDA panel, there’s data from TransMedics studies that suggest myocardial edema...whether the data will ultimately support this is still being hotly debated at transplant meetings...there still remains skepticism about pumping organs...and increasing the ischemic time...the data that surrounds OCS, does the patient really benefit, and is there truly no hard done to that organ?”",
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      "text": "Likely harm and no proven benefit from TransMedics pump for heart or lung. Lung is marginal, whether pumping the lung is a good thing. There are concerns with pumping a heart for a long period of time. A pump is not a benign thing.",
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      "text": "Surgeon on FDA panel that approved heart device barely uses it anymore. I am a cardiac surgeon. Our program does about 60 heart transplants a year... We use TransMedics in 10-12% of our cases a year.",
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      "text": "\"I am a cardiac surgeon. Our program does about 60 heart transplants a year. We do not do lung transplants. We do Impeller liver transplants; I’m not involved in those. We use TransMedics in 10-12% of our cases a year. For disclosure, I was on the FDA panel that voted to approve TransMedics, so I’m very familiar with that product. We began to use it about two years ago.\" — Cardiac transplant surgeon at a major Midwest academic center",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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