{
  "docId": "019dd923-622c-750b-8b9a-40e2965928db",
  "docSlug": "e5bffbaac707",
  "documentTitle": "TransMedics (TMDX)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
  "documentKindSlug": "research-note",
  "documentKindLabel": "Research note",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2025-01-10 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.3333334,
  "pageNumber": 101,
  "pageCount": 342,
  "prevPage": 100,
  "nextPage": 102,
  "slideType": "villain_critique",
  "function": "expose_contradiction",
  "density": "balanced",
  "nDataPoints": 0,
  "notes": "The slide uses a skeptical tone to challenge the scientific validity of the claims presented in the video.",
  "elementsJson": [
    "paragraph",
    "photo"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b9a-40e2965928db/101",
  "deckHref": "/decks/019dd923-622c-750b-8b9a-40e2965928db",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-40e2965928db.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-40e2965928db#slide-101",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "The claims for machine perfusion become increasingly preposterous: “we can convert different blood types to an O blood type...we can actually make changes in the genetic makeup of the donor organ...we can add genes...silence genes...those foreign proteins that were the cause of rejection.”",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-5373-719d-a978-dc70b8f58c9a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.45,
        "w": 0.86,
        "x": 0.07,
        "y": 0.48
      },
      "kind": "image",
      "text": null,
      "attrs": null,
      "subkind": "photo",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "c0b4eec2-ab22-42e3-af4e-d0c56d208b2d",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.35,
        "w": 0.86,
        "x": 0.07,
        "y": 0.07
      },
      "kind": "paragraph",
      "text": "In his TED talk, Ardehali suggests one can put pneumonia-infected lungs on the OCS pump which “can actually repair a donor organ” with supernormal doses of antibiotics that would cause “toxicities” in the donor – transplanting infected lungs strikes us a good way to lose one’s medical license and be sued out of business for malpractice. Moreover, we are curious how the TransMedics pump protects lung cells and tissue from doses so high that they would harm the rest of a donor’s body. The claims for machine perfusion become increasingly preposterous: “we can convert different blood types to an O blood type...we can actually make changes in the genetic makeup of the donor organ...we can add genes...silence genes...those foreign proteins that were the cause of rejection.”",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "06efd295-62f0-44b1-900d-a4a882c331c4",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "“we can convert different blood types to an O blood type...we can actually make changes in the genetic makeup of the donor organ...we can add genes...silence genes...those foreign proteins that were the cause of rejection.” — Dr. Abbas Ardehali",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd953-5373-719d-a978-e2a70028de0a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.02,
        "w": 0.25,
        "x": 0.07,
        "y": 0.44
      },
      "kind": "source-note",
      "text": "TED talk by Dr. Ardehali, Dec 2023 – video stills",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "d3f27f95-24dc-440a-8528-bf25177aa1be",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.02,
        "w": 0.65,
        "x": 0.07,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Source: https://www.ted.com/talks/abbas_ardehali_the_miracle_of_organ_donation_and_a_breakthrough_for_the_future/transcript?subtitle=en",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "f96657fa-a4f9-4846-9330-bc5a2574d94b",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}