{
  "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583",
  "docSlug": "f06b0b5d2079",
  "documentTitle": "Soleno Therapeutics (SLNO)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
  "documentKindSlug": "activist-deck",
  "documentKindLabel": "Activist deck",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2025-08-15 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.3333334,
  "pageNumber": 97,
  "pageCount": 415,
  "prevPage": 96,
  "nextPage": 98,
  "slideType": "testimonial",
  "function": "expose_contradiction",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "The slide uses direct quotes to undermine the clinical value and safety profile of the drug.",
  "elementsJson": [
    "headline_text",
    "bullet_list",
    "footnote"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/97",
  "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-97",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "I think that the severity of edema and cardiac risk probably is being underplayed. The risks are real and significant, and probably underplayed to some degree, and the benefit is mild at best...I am a little bit surprised about the approval",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-64ce-7561-b29d-c31b4e4d5112",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.285,
        "w": 0.848,
        "x": 0.076,
        "y": 0.575
      },
      "kind": "list",
      "text": "Indicated that he was surprised at FDA approval; that edema and cardiac risks are “real and significant” and “being underplayed”; that the drug is basically useless.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b6d77919-5b70-49f0-8031-ff1465add18a",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.165,
        "w": 0.848,
        "x": 0.076,
        "y": 0.405
      },
      "kind": "list",
      "text": "Stated that it is “very, very logical” that Vykat would amplify diabetes risk in already vulnerable PWW patients, given its mechanism of action.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "bc0b64eb-7171-4efc-8bcf-b63563f38d38",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.235,
        "w": 0.848,
        "x": 0.076,
        "y": 0.165
      },
      "kind": "list",
      "text": "Emphasized that he would just use generic diazoxide if Vykat had any value in PWS, and indicated that he substitutes inexpensive generic GLP-1's all the time vs. branded versions.",
      "attrs": null,
      "subkind": "bullet",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "fd1418d1-3b5f-4da3-a6c1-1300c31b3bfd",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "“I've always known that there was a generic diazoxide agent” and that if did seem to help anyone, that “then I probably going to use the generic in all of those patients... I'm probably going to switch everybody over to the generic anyway...I was willing to give the branded option a try on that first one, see what it's like, and get a little experience with it...but long-term, definitely not...why would you do that?”; “it's not like it's that hard to figure out...the \"what do you do\" is pretty straightforward...I would just go with generic diazoxide.” — PWS endocrinologist #9",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd953-64ce-7561-b29d-c619e1ec2152",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.02,
        "w": 0.305,
        "x": 0.076,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Source: Scorpion Capital consultation calls with experts",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "b730fafe-3170-465c-b757-bff76e22fc7e",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.065,
        "w": 0.848,
        "x": 0.076,
        "y": 0.073
      },
      "kind": "title",
      "text": "PWS endocrinologist #9 (cont’d): In private practice in a major Texas metropolitan area with 4 endocrinologists",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "619fffe2-a1bf-4e3c-bd08-1921c26049c9",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}