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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses direct quotes to highlight the physician's lack of confidence in the drug and his perception of external pressure from patient advocacy groups.",
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      "text": "The endocrinologist appeared so skittish at our questions - \"you're making me a little concerned about this\" - that he encouraged us and/or skeptical trial investigators to go public with our concerns as soon as possible.",
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      "text": "As the call progressed, the endocrinologist appeared so skittish at our questions - \"you’re making me a little concerned about this\" - that he encouraged us and/or skeptical trial investigators to go public with our concerns as soon as possible.",
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      "text": "He indicated he has heard no enthusiasm for Vykat from endocrinologists, and that he submitted some start forms only because the parents pushed for it - \"three of the patients actually asked me about the drug and were really requesting their kids to be on the drug...\"",
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      "text": "He started the call sounding open to Vykat - although he noted the phase 3 trial was a failure - but quickly became rattled - perhaps even panicked, as he’s already submitted start forms - at our line of inquiry, and seemed to wonder if he had been fleeced.",
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      "text": "The endocrinologist indicated little enthusiasm from doctors, and stated that parents were pushing for it after being marketed to by a Prader-Willi foundation, emphasizing the need for more honest color from the study investigators.",
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      "text": "Has submitted 5 Vykat start forms with one denial and four unapproved as insurers stall, stating he only did so because 1) a few parents pushed for it after being hyped up by a PWS association and it’s hard to say no; and 2) he was sold by Jennifer Miller.",
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      "text": "\"one patient with good commercial insurance who just got denied...other four at pending...we don't know what's going on with them at this point...we're relying on the specialty pharmacy to do the appeal.\" — Endocrinologist #5",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "Endocrinologist #5: Division Chief for pediatric endocrinology at a major academic center who sees 20-25 PWS patients annually.",
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