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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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      "text": "Diazoxide has only 2 key direct actions in the periphery and none in the CNS: 1) decrease insulin 50-90%... 2) increase fluid retention...",
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      "text": "While diazoxide does not reach the brain, it does have extensive peripheral effects via suppressing circulating insulin >50% and fluid retention. In PWS, low insulin will increase insulin resistance, increase hyperphagia, increase fatigue, and increase diabetes.",
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