{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 401, "pageCount": 415, "prevPage": 400, "nextPage": 402, "slideType": "quote_slide", "function": "expose_contradiction", "density": "dense", "nDataPoints": 0, "notes": "The slide uses a direct quote to undermine the perceived value of the drug.", "elementsJson": [ "paragraph", "quote_block", "footnote" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/401", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-401", "components": [ { "bbox": null, "kind": "callout", "text": "Vykat is “old news” as endocrinologists are very familiar with diazoxide; not “a brand new medication”; if any families are actually interested in Vykat, then will have to educate them on the safety issues with diazoxide", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64cf-7128-a313-c23f36142746", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.25, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "paragraph", "text": "The endocrinologist stated diazoxide is “old news” and that he would “switch everybody over to the generic anyway” if he thought it had any benefit in PWS: “it's not particularly powerful...diazoxide is not, in and of itself, a brand-new medication...it's a drug that we've used in other disease states for years... the actual drug has been approved for many years to be used in other diseases...many people have been put on it previously...we actually know this stuff pretty well because it's a drug that's been out for a while....”", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "2ae41f41-5c30-42cf-885b-5e70c1772377", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.55, "w": 0.86, "x": 0.07, "y": 0.35 }, "kind": "quote", "text": "Vykat is “old news” as endocrinologists are very familiar with diazoxide; not “a brand new medication”; if any families are actually interested in Vykat, then will have to educate them on the safety issues with diazoxide. “And I do think that the data is — I'd rather have something than nothing, but it's not particularly powerful. And if I am going to do the medicine, I do want to have some familiarity. I guess I kind of already do. Diazoxide is not, in and of itself, a brand-new medication. It's a drug that we've used in other disease states for years. At least I have some familiarity on the safety, and that family didn't specifically about ask about this. They were just like, let me think about it. We'll talk about it at our next appointment. Fine. Very fair. If they had been asking a little bit more questions, then I might have been like, okay, well, here's the information about how the drug works. It's a new medicine in that it was approved for this condition very recently. But the actual drug has been approved for many years to be used in other diseases. Many people have been put on it previously...we actually know this stuff pretty well because it's a drug that's been out for a while...” - Endocrinologist in TX, private practice with 5 PWS patients", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "cbf2018e-365e-4d63-8e5c-f419af429c2a", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“And I do think that the data is — I'd rather have something than nothing, but it's not particularly powerful. And if I am going to do the medicine, I do want to have some familiarity. I guess I kind of already do. Diazoxide is not, in and of itself, a brand-new medication. It's a drug that we've used in other disease states for years. At least I have some familiarity on the safety, and that family didn't specifically about ask about this. They were just like, let me think about it. We'll talk about it at our next appointment. Fine. Very fair. If they had been asking a little bit more questions, then I might have been like, okay, well, here's the information about how the drug works. It's a new medicine in that it was approved for this condition very recently. But the actual drug has been approved for many years to be used in other diseases. Many people have been put on it previously...we actually know this stuff pretty well because it's a drug that's been out for a while...” — Endocrinologist in TX, private practice with 5 PWS patients", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64cf-7128-a313-c7d3a96dd98c", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.3, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "383058de-b9ec-4b6e-91b4-9da2e8bd393b", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "ceo-quote-contradiction", "slug": null, "matchId": "7925d77c-fee4-492a-9520-a5bfd9353d92", "evidence": "Uses expert testimony to contradict the value proposition of a drug.", "confidence": 0.9 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }