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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "authorName": "Scorpion Capital",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses a combination of narrative summary and direct Q&A transcript excerpts to build a case of potential clinical trial misconduct.",
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      "text": "Everything here is a black box - we couldn't even locate the CDER review package, last we looked.",
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      "text": "A handful of trial sites enrolled a substantial percentage of patients for phase 3 and the withdrawal study. A: “Jennifer Miller was the biggest enroller... Q: “And do you remember roughly how many patients the top three had? ... A: “I think Felner and Miller probably had... 20 to 30 of them.”",
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      "text": "Everything here is a black box - we couldn't even locate the CDER review package, last we looked. Three ex-employees, two of whom were closely involved in the clinical trials, indicated that enrollment was heavily weighted to one site - Jennifer Miller - plus two others, and that they were suspicious of Miller's behavior.",
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      "text": "We can locate no peer-reviewed publication for the withdrawal study, highly unusual for an FDA-approved drug and a massive red flag. We therefore presume the paper wouldn't pass peer review, or that Soleno wishes to conceal the data from the public.",
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      "text": "“Miller was the biggest enroller...I think Eric Felner was number 2”; “other than the top three, the rest of them had three or fewer”; “I think Felner and Miller probably had, out of the 77 that were in the withdrawal study, I think they probably had between 20 to 30 of them.” In the failed phase 3 study, the ex-employee estimated that the same top enrollers had “probably in the 40 to 50 ballpark between the three of them” out of ~127 total.",
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      "text": "“Jennifer Miller was the biggest enroller. I think Eric Felner was number two. And the third largest was a lady over in the UK. Nicola Bridges. She was the third top enroller.” — Formerly in a senior medical affairs role at Soleno",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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