{
  "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583",
  "docSlug": "f06b0b5d2079",
  "documentTitle": "Soleno Therapeutics (SLNO)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
  "documentKindSlug": "activist-deck",
  "documentKindLabel": "Activist deck",
  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2025-08-15 00:00:00",
  "orientation": "landscape",
  "aspectRatio": 1.3333334,
  "pageNumber": 398,
  "pageCount": 415,
  "prevPage": 397,
  "nextPage": 399,
  "slideType": "testimonial",
  "function": "expose_contradiction",
  "density": "dense",
  "nDataPoints": 0,
  "notes": "The slide uses a Q&A format to expose the contradiction between the drug's intended use and its actual clinical viability.",
  "elementsJson": [
    "paragraph",
    "quote_block"
  ],
  "metadataConfidence": 1,
  "imagePath": null,
  "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/398",
  "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583",
  "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json",
  "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-398",
  "components": [
    {
      "bbox": null,
      "kind": "callout",
      "text": "people may just say, let's try this other medication, just the regular diazoxide, which is not an ideal drug. Let me put it that way. We know that...",
      "attrs": null,
      "subkind": null,
      "toolName": "Visual emphasis",
      "toolSlug": "visual-emphasis",
      "confidence": null,
      "componentId": "019dd953-64ce-7561-b2b7-5c3e3fec6870",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.07,
        "w": 0.86,
        "x": 0.07,
        "y": 0.38
      },
      "kind": "paragraph",
      "text": "Can't give tablets to pediatric patients unless crushed; likely to try generic diazoxide suspension instead; pre-existing concerns about diazoxide - \"not an ideal drug, put it that way\"; same issues carry over to Vykat",
      "attrs": null,
      "subkind": "paragraph",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "a617ddc7-6583-418b-8a50-6ba9f263ea39",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.35,
        "w": 0.86,
        "x": 0.07,
        "y": 0.46
      },
      "kind": "quote",
      "text": "Q: \"So, if somebody wants to use Vykat, my question is, why would they just not use the oral suspension? How do you even prescribe a tablet to a five-year-old?\"\nA: \"You don't. That's the thing. Unless you're able to crush it and you're not supposed to, so to speak, crush the extended-release medications. That might become — if people see these trials and they get refusals with all the knowledge now that you shared, and I'm sure it's going to come up at some point. Perhaps as clinicians start experiencing some of this, or patients start experiencing some of these issues, people may just say, let's try this other medication, just the regular diazoxide, which is not an ideal drug. Let me put it that way. We know that...\"\nQ: \"That also means Vykat is not ideal. There are just different methods of administration of the same drug.\"\nA: \"Correct, yes, they are. And again, the only thing would be maybe that we would need to admit.\" - Pediatric endocrinologist",
      "attrs": null,
      "subkind": "testimonial",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "5dc5b998-1dc7-4138-b477-b445416c1cf5",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": null,
      "kind": "quote",
      "text": "You don't. That's the thing. Unless you're able to crush it and you're not supposed to, so to speak, crush the extended-release medications. That might become — if people see these trials and they get refusals with all the knowledge now that you shared, and I'm sure it's going to come up at some point. Perhaps as clinicians start experiencing some of this, or patients start experiencing some of these issues, people may just say, let's try this other medication, just the regular diazoxide, which is not an ideal drug. Let me put it that way. We know that... — Pediatric endocrinologist",
      "attrs": null,
      "subkind": null,
      "toolName": "Authority citation",
      "toolSlug": "authority-citation",
      "confidence": null,
      "componentId": "019dd953-64ce-7561-b2b7-6135d908ed01",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.02,
        "w": 0.3,
        "x": 0.07,
        "y": 0.95
      },
      "kind": "source-note",
      "text": "Source: Scorpion Capital consultation calls with experts",
      "attrs": null,
      "subkind": null,
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "ee7e3ae2-39a2-459b-b164-c51b12cc9f44",
      "frameworkName": null,
      "frameworkSlug": null
    },
    {
      "bbox": {
        "h": 0.25,
        "w": 0.86,
        "x": 0.07,
        "y": 0.07
      },
      "kind": "title",
      "text": "The endocrinologist expressed concern about Vykat’s tablet formulation, when we asked how one even prescribes a tablet to a 5-year old - \"You don't...that's the thing...unless you're able to crush it and you're not supposed to\" given the extended-release formulation - and assumed that physicians would just move to generic diazoxide suspension instead: \"people may just say, let's try...just the regular diazoxide, which is not an ideal drug, let me put it that way...we know that...maybe we would need to admit\" that Vykat and the generic suspension are the same.",
      "attrs": null,
      "subkind": "headline",
      "toolName": null,
      "toolSlug": null,
      "confidence": null,
      "componentId": "e559820a-5d60-4b53-a864-76d3e3fd6db4",
      "frameworkName": null,
      "frameworkSlug": null
    }
  ],
  "metrics": [],
  "tools": [],
  "frameworks": [],
  "arcBeats": [],
  "loops": [],
  "imagePathAlt": null,
  "thumbSrc": null,
  "thumbSrcAlt": null,
  "locked": true
}