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  "documentTitle": "Soleno Therapeutics (SLNO)",
  "authorId": "58_Scorpion_Capital",
  "authorName": "Scorpion Capital",
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  "sourceTypeSlug": "short_seller",
  "sourceTypeLabel": "Short seller",
  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses a Q&A format to highlight the physician's reluctance to prescribe Vykat and their familiarity with the risks of diazoxide.",
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      "text": "We are going to wait...we are going to wait...we have not met with their medical science liaison.",
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      "text": "Pediatric endocrinologist with 5 PWS patients; academic and community practice\nQ: “It looks like you're based in South Carolina and are a pediatric endocrinologist. How many Prader-Willi patients do you currently manage?”\nA: “Five. I was not been an investigator, and I was not involved in any manuscripts and papers. I am just aware of it as a physician, as a pediatric endocrinologist, managing Prader-Willi Syndrome patients.”\nQ: “And are you a community physician, or are you at an academic center?”\nA: “I am a pediatric board-certified pediatric endocrinologist, and I work in the tertiary children's hospital that's affiliated with the medical academic center and medical school.” – Pediatric endocrinologist",
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      "text": "Endocrinologists are extremely familiar with diazoxide already; concerned about diabetes risk\n“As pediatric endocrinologists, we are familiar with the short-acting form of diazoxide. We have used that for quite some time for our patients with congenital hyperinsulinism. We are familiar with the drug itself. But some side effects that have been a concern...it mostly may present as a lymphedema versus congestive heart failure that we are worried more in our newborns. Hyperglycemia, again, we know that diazoxide causes it.” – Pediatric endocrinologist",
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      "text": "No start forms submitted; “we are going to wait”; no outreach from Soleno MSL to address their questions/concerns\nQ: “Have you submitted any forms for any of your 5 or 6 patients yet to get Vykat, or are you going to wait?”\nA: “We are going to wait...we are going to wait. We have not met with their medical science liaison. They have not expressed interest so far to come and talk to us, and we have not met the rep. Unfortunately, we have not met the people yet.” –Pediatric endocrinologist",
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      "text": "As pediatric endocrinologists, we are familiar with the short-acting form of diazoxide...we have used that for quite some time...with congenital hyperinsulinism.... side effects that have been a concern...it mostly may present as a lymphedema versus congestive heart failure; hyperglycemia...we know that diazoxide causes it. — Pediatric endocrinologist",
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      "kind": "source-note",
      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "PWS endocrinologist #8: At a “children's hospital that's affiliated with a medical academic center and medical school” in the southeast US; has 5 PWS patients personally. No patient start forms submitted at the institution and indicated high skepticism of Vykat with no interest in meeting Soleno drug rep. Stated that diazoxide is an old compound well-known to endocrinologists, with risk of hyperglycemia and edema – “We are going to wait...we are going to wait...we have not met with their medical science liaison”; “as pediatric endocrinologists, we are familiar with the short-acting form of diazoxide...we have used that for quite some time...with congenital hyperinsulinism.... side effects that have been a concern...it mostly may present as a lymphedema versus congestive heart failure”; “hyperglycemia...we know that diazoxide causes it.”",
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