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      "text": "it's a very big concern...bananas...you're blocking insulin production in kids who are prone to obesity and diabetes.",
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      "text": "He expressed similar concern about potentially fatal cardiac risk, citing a previous case of heart failure after he treated a child with diazoxide, and that his concern increased after we asked about Vykat-driven channelopathy risks by PWS subtype.",
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      "text": "Extremely concerned about diabetes risk – “bananas, Q: “What is your thought on the diabetes issue here?” A: “No, it's a very big concern. And my professor would have used the term bananas. My most important mentor...you're blocking insulin production in kids who are prone to obesity and diabetes.” - Pediatric endocrinologist, division chief at an academic center",
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      "text": "Highly concerned about cardiac risk; recent child he put on diazoxide experienced “mild” cardiac failure Q: “How do you think about cardiac risk? Were you aware of it, or was this a topic of discussion at these endo meetings?” A: “Yeah, certainly I'm aware of it. Actually, one of the last kids who I treated for hyperinsulinism, who had big-time insulin doses, i was fairly aggressive, and I put the kid into mild failure. Thankfully, we've got great cardiologists, and we started a diuretic when we start diazoxide, and we always do a pre-treatment echocardiogram. Again, these kids are at cardiac risk based on their weight to start with.” - Pediatric endocrinologist, division chief at an academic center",
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      "text": "Hypertrichosis is a “certainly real” side effect; concerned about edema/cardiac risk across PWS genetic subtypes Q: “So, they're producing too much insulin, blood sugar goes down. Then you give them diazoxide to suppress the insulin.” A: “Right. I've been doing that since I was a fellow. And the hypertrichosis is certainly real. The dose is lower. And they argue that it's a salt, and the dose is lower. I was unaware that there are different channelopathies that develop based on your Prader-Willi mutation. But if that's true, and nephrologists are much smarter than endocrinologists, that would certainly increase my concern.” - Pediatric endocrinologist, division chief at an academic center",
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      "text": "\"it's a very big concern...bananas...you're blocking insulin production in kids who are prone to obesity and diabetes.\" — Pediatric endocrinologist, division chief at an academic center; \"Yeah, certainly I'm aware of it. Actually, one of the last kids who I treated for hyperinsulinism, who had big-time insulin doses, i was fairly aggressive, and I put the kid into mild failure.\" — Pediatric endocrinologist, division chief at an academic center; \"I was unaware that there are different channelopathies that develop based on your Prader-Willi mutation...But if that's true, and nephrologists are much smarter than endocrinologists, that would certainly increase my concern.\" — Pediatric endocrinologist, division chief at an academic center",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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