{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 381, "pageCount": 415, "prevPage": 380, "nextPage": 382, "slideType": "quote_slide", "function": "expose_contradiction", "density": "overcrowded", "nDataPoints": 0, "notes": "The slide uses direct quotes from an expert consultation to contrast grassroots patient enthusiasm with professional indifference.", "elementsJson": [ "paragraph", "quote_block", "footnote" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/381", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-381", "components": [ { "bbox": null, "kind": "callout", "text": "The buzz is only amongst people in the quote-unquote, Prader-Willi community. Maybe some pediatric endocrinologists that aren't part of an academic center have like 1 or 2 patients, and so they're interested in learning more. But people positioned like me are probably prescribing it, but with some question about how successful it's going to be.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2b6-40fe7f30013f", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.08, "w": 0.86, "x": 0.07, "y": 0.57 }, "kind": "paragraph", "text": "No buzz or chatter about Vykat at recent key annual endocrinologist meeting; some people probably prescribing it \"but with some question about how successful it's going to be\"; didn't bother to attend any Vykat sessions", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "9c635416-a7fd-4926-b803-36cf3105fd17", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.08, "w": 0.86, "x": 0.07, "y": 0.41 }, "kind": "paragraph", "text": "Patient enthusiasm driven mainly by Facebook PWS groups; \"been wanting to start it as soon as it was released\"", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "a8292b46-db48-43ac-8a91-0a266bcc14d8", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.12, "w": 0.86, "x": 0.07, "y": 0.44 }, "kind": "quote", "text": "\"I would say that many of my patients are on Facebook groups and so on. That type of family is aware that Vykat is available. They were aware that it was going to be available before it was available. They've been excited for it. They've been wanting to start it as soon as it was released.\" - Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "10dea69d-c45f-46a8-b100-9de77c429bed", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.28, "w": 0.86, "x": 0.07, "y": 0.65 }, "kind": "quote", "text": "Q: \"Were you at the endocrinology meeting the other week? The big annual one?\" A: \"Yes.\" Q: \"And how much buzz or excitement there was on Vykat, or has it been pretty muted?\" A: \"First of all, I'd say the average pediatric endocrinologist doesn't care because they don't have any patients with Prader-Willi Syndrome. The buzz is only amongst people in the quote-unquote, Prader-Willi community. Maybe some pediatric endocrinologists that aren't part of an academic center have like 1 or 2 patients, and so they're interested in learning more. But people positioned like me are probably prescribing it, but with some question about how successful it's going to be.\" Q: \"But this wasn't like chatter in the hallways among PWS people at the meeting?\" A: \"I wouldn't say that.\" Q: \"And if you had to rank the level of enthusiasm or discussion among PWS people at the annual meeting, the big PWS people for Vykat, on a scale of 1 to 10, what do you think that enthusiasm or excitement level was that you observed?\" A: \"I didn't attend any of the Vykat sessions.. I didn't personally talk to anybody about Vykat at the conference.\" - Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "cebcca46-2cd1-47df-a705-98e938a409d1", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“I would say that many of my patients are on Facebook groups and so on...they've been excited for it...they've been wanting to start it as soon as it was released” — Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center. “I didn't attend any of the Vykat sessions.. I didn't personally talk to anybody about Vykat at the conference...” — Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center.", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2b6-464882ea4c8c", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.3, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "ce88e27f-b386-48fa-8631-72e5fcc0b99f", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.18, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "title", "text": "The endocrinologist stated that families pushing for Vykat have been hyped up on Facebook groups, but that endocrinologists who actually treat meaningful numbers of PWS patients are skeptical, indicating no buzz or chatter at the recent Pediatric Endocrine Society meeting", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "4828c6f7-4795-4d8e-9c86-46810cc3c1e0", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }