{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 378, "pageCount": 415, "prevPage": 377, "nextPage": 379, "slideType": "testimonial", "function": "expose_contradiction", "density": "dense", "nDataPoints": 3, "notes": "The slide uses a 'before-after' narrative structure to expose the contradiction between the physician's initial interest and his clinical assessment.", "elementsJson": [ "paragraph", "quote_block" ], "metadataConfidence": 0.95, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/378", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-378", "components": [ { "bbox": null, "kind": "callout", "text": "The hour-long interview note started on a bullish note for Soleno as he has submitted 15 start forms, and then quickly collapsed as he confessed that he thinks the drug has minimal benefit and the data is “marginal”.", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2b5-e08c9fde3b93", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.38, "w": 0.86, "x": 0.07, "y": 0.2 }, "kind": "paragraph", "text": "“I’m very familiar with Vykat...I was monitoring all of the clinical trials and read all the publications...I feel like I know pretty much everything there is to know about Vykat.” The hour-long interview note started on a bullish note for Soleno as he has submitted 15 start forms, and then quickly collapsed as he confessed that he thinks the drug has minimal benefit and the data is “marginal”; that this “a drug that could give them diabetes or edema or death”; that he only prescribed it because he can’t so no to desperate families that have been hyped up by Facebook groups and Jennifer Miller; that he feels “hypocritical” for caving in to pressure to prescribe given his reservations; and that of the 15 start forms he’s submitted, most have been denied with few approvals – “the parents are burnt out and really looking for anything...and so, the hype around any new medicine coming out has been very high...”", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6b665776-7598-4097-ab5a-a0ed4e06cace", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.12, "w": 0.86, "x": 0.07, "y": 0.63 }, "kind": "quote", "text": "“I work at a university-based pediatric hospital, and I’m one of 11 pediatric endocrinologists, but we have a Prader-Willi Syndrome clinic, and I’m the [redacted] pediatric endocrinologist in that clinic. I pretty much see all the patients with PWS that come to our pediatric hospital. And so that means about 30 to 40 Prader-Willi patients that I take care of...I’m very familiar with Vykat. I was monitoring all of the clinical trials and read all the publications...I feel like I know pretty much everything there is to know about Vykat.”", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0af15e1a-4cbe-4d2c-9df5-7f88dbd47083", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.06, "w": 0.86, "x": 0.07, "y": 0.82 }, "kind": "quote", "text": "“This condition is so problematic mostly from a behavioral standpoint, the parents are burnt out and really looking for anything. And so, the hype around any new medicine coming out has been very high...”", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "dd7c86fc-c981-4254-a9f4-609a3197ff94", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“I’m very familiar with Vykat...I was monitoring all of the clinical trials and read all the publications...I feel like I know pretty much everything there is to know about Vykat.” — Pediatric endocrinologist, leads one of the largest PWS clinics in US with 30-40 patients; 11 endocrinologists, major academic center", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2b5-e76439927740", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.3, "x": 0.07, "y": 0.95 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "979df15c-0ef8-4a7d-9321-6f600fcc9a03", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.12, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "title", "text": "PWS endocrinologist #6: Lead pediatric endocrinologist at a major academic center, one of the largest PWS clinics in the US with 30-40 patients and 11 endocrinologists", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "ed822508-658f-4bca-b4d4-7e21fbd38ef5", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "ceo-quote-contradiction", "slug": null, "matchId": "9f71d9c1-bd29-47e5-b794-5cd505adba0c", "evidence": "The slide explicitly contrasts the physician's initial bullishness with his subsequent clinical dismissal of the drug.", "confidence": 0.9 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }