{ "docId": "019dd923-622c-750b-8b9a-3bcd52c6e583", "docSlug": "f06b0b5d2079", "documentTitle": "Soleno Therapeutics (SLNO)", "authorId": "58_Scorpion_Capital", "authorName": "Scorpion Capital", "documentKindSlug": "activist-deck", "documentKindLabel": "Activist deck", "sourceTypeSlug": "short_seller", "sourceTypeLabel": "Short seller", "presentationDate": "2025-08-15 00:00:00", "orientation": "landscape", "aspectRatio": 1.3333334, "pageNumber": 359, "pageCount": 415, "prevPage": 358, "nextPage": 360, "slideType": "testimonial", "function": "expose_contradiction", "density": "overcrowded", "nDataPoints": 0, "notes": "The slide uses direct quotes to undermine the credibility of the company's sales representatives and the drug's market reception.", "elementsJson": [ "paragraph", "quote_block", "footnote" ], "metadataConfidence": 1, "imagePath": null, "slideHref": "/slides/019dd923-622c-750b-8b9a-3bcd52c6e583/359", "deckHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583", "deckJsonHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583.json", "deckAnchorHref": "/decks/019dd923-622c-750b-8b9a-3bcd52c6e583#slide-359", "components": [ { "bbox": null, "kind": "callout", "text": "Most endocrinologist taking a “wait and see” attitude to Vykat; some “may give it a try” if “a family that's really advocating”", "attrs": null, "subkind": null, "toolName": "Visual emphasis", "toolSlug": "visual-emphasis", "confidence": null, "componentId": "019dd953-64ce-7561-b2b4-a110ec0d988c", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.86, "x": 0.07, "y": 0.46 }, "kind": "paragraph", "text": "No enthusiasm for Vykat at recent Pediatric Endocrine Society Meeting", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "43e10800-9408-49b0-8b89-c0a57d275741", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.86, "x": 0.07, "y": 0.33 }, "kind": "paragraph", "text": "Soleno rep's extreme examples of hyperphagia patients were unrealistic", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "710748a6-b0ef-4e99-a88b-c0ef3b02bd46", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.03, "w": 0.86, "x": 0.07, "y": 0.62 }, "kind": "paragraph", "text": "Most endocrinologist taking a “wait and see” attitude to Vykat; some “may give it a try” if “a family that’s really advocating”", "attrs": null, "subkind": "paragraph", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "9c517855-8948-40f6-9bb7-a3a5896792a6", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.15, "w": 0.86, "x": 0.07, "y": 0.65 }, "kind": "quote", "text": "“I think most people are wait-and-see. I think if somebody has some profound hyperphagia and they don't feel like there's other options, then I think people will give it a try, particularly if you have a family that's really advocating. I think when you're looking at a family, and they are really struggling — I have patients with hypothalamic obesity after brain cancer...if there are barriers to getting the medication, it's really hard. Anytime there's something new, people are usually less comfortable with it. And when I think about the idea of something that could cause someone to have diabetes versus something else.” - Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "0555047d-3c62-471b-b0ea-f99a0a37f934", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.11, "w": 0.86, "x": 0.07, "y": 0.49 }, "kind": "quote", "text": "Q: “How did this meeting with the Soleno drug rep go?”\nA: “I can say, in our group, there weren't a lot of big questions. I did go to the Pediatric Endocrine Society meeting a few weeks ago, and I sat next to someone who's done a lot of this research - I did fellowship at CHOP, and I can say the people around the table, I sat with some people that I knew from fellowship, and most of them were not super impressed.” - Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "6c94bb5a-740f-4458-a3bd-fbb29b75ed89", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.08, "w": 0.86, "x": 0.07, "y": 0.36 }, "kind": "quote", "text": "“And it was locking up the cabinets kind of thing. A lot of the stories that the reps provided with us on Wednesday aren't things that I'm seeing right now with my patients. But most of my patients are younger. I don't have any kids that are older. And usually, the hyperphagia develops around age of 8 and can develop earlier\" - Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients", "attrs": null, "subkind": "testimonial", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "88758679-6152-43c5-85fc-54418ac6a09b", "frameworkName": null, "frameworkSlug": null }, { "bbox": null, "kind": "quote", "text": "“the stories that the reps provided with us...aren't things that I'm seeing right now with my patients” — Pediatric endocrinologist at a Delaware academic center", "attrs": null, "subkind": null, "toolName": "Authority citation", "toolSlug": "authority-citation", "confidence": null, "componentId": "019dd953-64ce-7561-b2b4-a4dea7cbf2d0", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.02, "w": 0.3, "x": 0.07, "y": 0.91 }, "kind": "source-note", "text": "Source: Scorpion Capital consultation calls with experts", "attrs": null, "subkind": null, "toolName": null, "toolSlug": null, "confidence": null, "componentId": "8c60fd80-8dcd-4382-a65c-a724ef70b5bd", "frameworkName": null, "frameworkSlug": null }, { "bbox": { "h": 0.25, "w": 0.86, "x": 0.07, "y": 0.07 }, "kind": "title", "text": "Endocrinologist #4 stated that “the stories that the reps provided with us...aren't things that I'm seeing right now with my patients” as far as hyperphagia. He indicated no enthusiasm for Vykat at the recent Pediatric Endocrine Society Meeting among endocrinologists familiar with diazoxide and “most of them were not super impressed”; that most other physicians were taking a “wait and see” attitude; that some “may give it a try” if “a family that’s really advocating” for it; but that concern about a drug “that could cause someone to have diabetes” is a driver of tepid interest – “I did go to the Pediatric Endocrine Society meeting... people around the table, I sat with some people that I knew from fellowship, and most of them were not super impressed....”", "attrs": null, "subkind": "headline", "toolName": null, "toolSlug": null, "confidence": null, "componentId": "678e1555-525e-4744-a62b-4121bf317fa8", "frameworkName": null, "frameworkSlug": null } ], "metrics": [], "tools": [], "frameworks": [ { "name": "fraud-exposure", "slug": null, "matchId": "5aa3a07d-6013-47fd-b829-76dbb536132b", "evidence": "The slide uses expert testimony to directly contradict company sales claims.", "confidence": 0.8 } ], "arcBeats": [], "loops": [], "imagePathAlt": null, "thumbSrc": null, "thumbSrcAlt": null, "locked": true }