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  "documentTitle": "Soleno Therapeutics (SLNO)",
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  "presentationDate": "2025-08-15 00:00:00",
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  "notes": "The slide uses a Q&A transcript format to highlight low adoption rates and physician skepticism.",
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      "text": "The endocrinologist indicated extreme skepticism of Vykat, stating that all 8 colleagues met with the Soleno rep a few weeks ago, with only one start form submitted between them across 50 patients, which hasn't gotten insurance approval.",
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      "text": "Academic center in Delaware serving NJ, PA, MD; 8 endocrinologists with ~50 PWS patients",
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      "text": "A: “Yes. It wasn’t me; it was one of my colleagues. I think she was waiting to hear back on what happened. A couple of my patients are young, and they don’t have hyperphagia. I’ve been following them since they were two months old for growth hormone. Whereas her patients are a little bit older...she just spoke up and shared because we know how this goes, sometimes, when newer things come out, everybody’s excited about it. But then if there’s a lot of hurdles for insurance and things like that, then people become less enthusiastic.” – Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients",
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      "text": "A: “No, we’re an academic center. We have a pretty robust residency program...a lot of us who trained, there’s four of us that trained at CHOP and diazoxide.” – Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients",
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      "text": "“four of us that trained at CHOP and diazoxide.” — Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients; “It wasn't me; it was one of my colleagues. I think she was waiting to hear back on what happened. A couple of my patients are young, and they don't have hyperphagia. I've been following them since they were two months old for growth hormone. Whereas her patients are a little bit older...she just spoke up and shared because we know how this goes, sometimes, when newer things come out, everybody's excited about it. But then if there's a lot of hurdles for insurance and things like that, then people become less enthusiastic.” — Pediatric endocrinologist at a Delaware academic center with eight endocrinologists and ~50 PWS patients",
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      "text": "Source: Scorpion Capital consultation calls with experts",
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      "text": "PWS endocrinologist #4: At an academic center with 8 endocrinologists who manage ~50 PWS patients; personally manages 5 patients, and indicated a significant number of his colleagues trained at CHOP and are thus highly experienced with diazoxide, as CHOP is the leading user for hyperinsulinism – “four of us that trained at CHOP and diazoxide.” The endocrinologist indicated extreme skepticism of Vykat, stating that all 8 colleagues met with the Soleno rep a few weeks ago, with only one start form submitted between them across 50 patients, which hasn’t gotten insurance approval: “It wasn’t me; it was one of my colleagues....we know how this goes...when newer things come out...then if there’s a lot of hurdles for insurance and things like that, then people become less enthusiastic.”",
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